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Drug diversion surveillance dashboard
Value Proposition Prescription drug diversion is defined as the illegal distribution or misuse of prescription medications. Drugs that are susceptible to abuse and addiction in at-risk individuals are commonly involved. In the light of nationwide…
A universal antidote for aptamer therapeutics
Value Proposition With an ever increasing number of people taking numerous medications, the need to safely administer drugs and limit unintended side effects has never been greater. Antidote control remains the most direct means to…
Whole eye optical coherence tomography scanner
Value proposition Optical Coherence Tomography (OCT) is an Optical imaging technique that provides 3D images of the subject of interest. OCT systems have been widely used to scan eyes for medical purposes. However, commercial OCT…
Components of the Wnt-Beta-catenin paracrine signaling pathway as predictive biomarkers for cancer immunotherapy
Value Proposition Immunotherapy is a promising approach for the treatment of many cancers. However, despite early success, majority of patients with advanced cancer fail to respond or become resistant. In even the most immunogenic cancer…
A deep machine learning algorithm to aid the diagnosis of cardiac transplant rejection
Value Proposition Transplant rejection remains a significant clinical concern following solid organ transplants, including cardiac transplantation. Although endomyocardial biopsy to diagnose cardiac allograft rejection is the gold standard of histologic grading of biopsy samples for…
RealChoices web-based menu planning and nutrition tracking computer software program
Value Proposition There are variable reasons why someone would seek a heathier food-related lifestyle. Unhealthy eating habits can have serios negative effects in one’s health. In America alone, it is estimated that over two-thirds of…
A software for more easily monitoring physiological data through improved visualization and machine learning analysis
Value Proposition With inexpensive wearable sensors, physiological data monitoring has extended beyond clinical anesthesia and emergency medicine and into in-home healthcare. Waveforms such as electrocardiography (ECG) and photoplethysmography (PPG) contain valuable information about a patient’s…
Antimicrobial prochelators to target drug-resistant bacteria
Value Proposition According to the CDC, each year 2.8 million people in the United States develop an antibiotic-resistant infection, leading to more than 35,000 deaths. Beta lactams were the largest segment in the antibiotics market…
Patient-centric mobile data-architecture for electronic health records
Value Proposition Most Electronic Health Records (EHR) solutions available today are centered around the needs of healthcare providers, in that they allow providers to manage records of their patients. Moreover, they rely on centralized data…
Pharmacometabolomic for drug response phenotypes in the study of cardiovascular disease and its treatment
The present invention concerns the application of lipidomics to statin treatment for disorders such as cardiovascular disorders. Hence, the invention provides, among other things, a method of correlating a lipid profile with a positive or…
Dopamine transporter knockout mouse
We have developed knockout mice lacking the dopamine transporter. These mice are hyperactive, and display cognitive abnormalities consistent with enhanced dopaminergic neurotransmission. They have a heightened dopaminergic state (increase dopamine activity), mimicking certain behaviors associated…
Targeting novel cytokine receptors for anti-cancer activity on human cancers
Researchers at Duke University have discovered novel mRNA isoforms of a cytokine receptor that are expressed in a variety of cancers, including breast and cervical cancer cells. They have created cell lines expressing these abnormal…