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Showing 4 matches for the following: Inventor: "Feng, Guoping" ×
GAD67-GFP mice
This line of transgenic mice expresses GFP in newly generated dentate granule cclls in the hippocampus, the most prominent site of adult neurogenesis. Adult neurogenesis has been shown lo play important roles in learning, memory…
Genes involved in the pathogenesis of anxiety disorders including obsessive-compulsive disorder
Anxiety disorders are the most common mental illness in the US, affecting 18% of the population. Obsessive compulsive disorder (OCD), in particular, is one of the most disabling with a diminished quality of life. Only…
Shank3 knockout mice as a model for autism
The Shank3B- knockout allele has a neo cassette replacing the PDZ domain (exons 13-16) of the Shank3 gene, resulting altered expression of the Shank3b isoform. These mice may be useful for studying behavioral abnormalities associated…
Stable Cell lines expressing nAChR subunits
About Nicotinic Acetylcholine Receptors (nAChR) Nicotinic acetylcholine receptors (nAChR) are receptor proteins that respond to the neurotransmitter acetylcholine, and respond to drugs including nicotine. When nAChR are activated, the cells release dopamine and other neurotransmitters,…