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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones
Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…
Rapid non-invasive optical assay system for intraoperative breast tumor margin assessment
Unmet Need Breast cancer is the most common non-skin cancer in women in the United States, accounting for 1 in 3 of all new female cancers each year. Breast conserving surgery is a common treatment…
On-chip waveguide optical isolator
Unmet Need Optical isolators are critically important in many applications in optical systems. Optical isolators are devices that transmit light in only one direction. They are used to avoid unwanted back-propagation of light, for example,…
A system for expanding the available photon energies in radiation therapy
Unmet Need Radiation treatments are mostly delivered using a medical linear accelerator (linac). Currently, because of the complexity of the linac engineering and the requirement of the dose rate output, the standard design of a…
SYMPHONY: Synergistic Immuno Photothermal Nanotherapy
Unmet Need Metastatic spread results in more than 90 percent of cancer deaths, and current therapeutic options, such as systemic chemotherapy, are often ineffective with harsh side effects. In recent years, immunotherapy using specific immune…
Producing and controlling the density of charged excitations in carbon nanotubes
Value Proposition Formation of quasiparticles, such as excitons, polarons, and trions in semiconductors are the foundation for modern optoelectronics. The trion, a three-body charge-exciton bound state, offers unique opportunities to simultaneously manipulate charge, spin, and…
Sparse aperture time of flight imaging
Value Proposition Millimeter wave imaging system have been widely used for security applications such as detecting concealed weapons and obstruction under low visibility conditions. Many current airport scanners perform holographic reconstruction of the target, but…
Systems and methods for ophthalmic surgical microscope mounted optical coherence tomography
Value Proposition Surgical visualization has changed drastically since its inception, incorporating larger, more advanced optics toward increasing illumination and field-of-view (FOV). However, the limiting factor in vitreoretinal surgery remains the ability to distinguish between tissues…
Coded aperture imaging photopolarimetry
An imaging polarimeter includes a polarization dispersing element, a spatial light modulator, a complementary polarization dispersing element, a polarization analyzer, an electronic detection plane, and a processor. The polarization dispersing element polarimetrically disperses an image…