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Platform for generating a seasonal vaccine for both influenza and coronaviruses
Unmet Need Similar to the flu vaccine, the need for seasonal post-immunization boosting to offer protection following COVID-19 vaccines remains possible. However, more than 8 percent of people who received a first dose of Pfizer…
Novel small molecule mast cell activator vaccine adjuvants
Value Proposition Mast cells (MCs) are innate immune cells highly prevalent in the dermal region of the skin and in the respiratory, gastrointestinal, and urinary tract mucosa. The strategic location at the host–environment interface and…
Sublingual immunization using supramolecular peptide-polymer conjugate tablets
Value proposition Immunization with vaccines prevent illness, disability, and currently avert an estimated 2 to 3 million deaths every year. However, commonly-used vaccine technology platforms can be unpredictable, require a high manufacturing cost, and often…
Replication competent bi- and tri-valent influenza viruses as vaccines
Value Proposition Influenza infection is a major public health concern, with an estimated 200,000 Americans hospitalized each year with flu or flu-related illness. The most effective method for flu prevention is vaccination, however, due to…
An adjuvant-free vaccine platform using self-assembling nanofibers
Value Proposition Vaccines have application for a wide range of human health conditions, including the treatment of pathogenic diseases, cancer immunotherapy, and the suppression of autoimmune disorders. In order to stimulate the immune system to…