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Chest Pain Assessment Tool (CPAT), a fast and convenient chest pain diagnosis decision aid software
Unmet Need Heart disease is the leading cause of death in the US. More than 7 million people present annually to emergency departments with symptoms of chest pain. Nearly 2% are misdiagnosed as not having…
GOPTICAS: Systems and methods for measurements of Gross Primary Production (GPP)
Unmet Need Over geological timescales, nearly half of the world’s atmospheric oxygen (O2) has been generated in the ocean by marine organisms such as algae, plankton and seaweed. These organisms synthesize oxygen based off the…
Identification and application of novel lipoglycodepsipeptide antibiotics
Unmet Need Antibiotic resistance (ABR) is a global public health concern. In 2019, an estimated five million deaths were attributed to antibiotic resistant pathogens. A recent study estimates that ABR could cause nearly ten million…
Advanced remote monitoring and prediction of deep-seated landslide risk using SAR and physical modeling
Unmet Need Deep-seated landslides are some of the most catastrophic natural hazards, gradually moving almost imperceptibly over many years before suddenly collapsing in a dramatic fashion. Conventional prediction methods depend on physical access through boreholes,…
A semiconducting material that switches between glass and crystalline states at lower temperatures than conventional inorganic semiconductors
Unmet Need In recent times, different forms of inorganic glasses have emerged that are distinct from what human civilization has been using for more than 5,000 years. Due to the advent of such glasses, a…
Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach
Unmet Need High-resolution three-dimensional (3D) imaging techniques have seen widespread adoption as a means by which to develop a real-time map of the world around us, such as is needed by a variety of autonomous…
Methods to implement three-dimensional (3D) sensing depth cameras
Unmet Need Real-time high-resolution three-dimensional (3D) imaging is highly desirable in a wide range of fields including biomedical imaging, robotics, virtual/augmented reality, 3D printing, and autonomous vehicles. To accomplish 3D imaging, sensing depth cameras have…
Vibrational Radar Backscatter Communications
Unmet Need The advent of autonomous driving powered by computational detection and assessment of vehicle surroundings by things like vision and radar has shown a lot of promise for self-driving vehicles. However, these systems can…
A User-Customizable Modular Microplate Holder
Unmet Need Globally, laboratory accessories had an estimated market value of $504.7 million in 2020. Microplates and accessories represent 16% of this global market, which totals to $80.7 million. Manufacturers sell a variety of microplates…
Novel ligand to target KRas-related cancers
Unmet Need Cancer is a serious health issue characterized by the abnormal growth of cells that invade and destroy healthy tissue. Nearly one in five human cancers features KRAS mutations, making it one of the…
Method for the in vitro differentiation of human dendritic cells from hematopoietic stem cells for research and immunotherapy development
Unmet Need Dendritic cells (DCs) play a critical role in the adaptive immune response by capturing and presenting antigens to activate cytotoxic T-cells. As such, naturally occurring DCs are thought to have crucial antitumor activity…
Gene signature for prediction of acute rejection in kidney transplant
Unmet Need Kidney transplant is the best current treatment for kidney failure. The kidney is the most common organ to be transplanted, and in 2019 there were 23,405 kidney transplants in the United States. Unfortunately,…