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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…

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Portable mass spectrometer with high sensitivity and resolution

Portable mass spectrometer with high sensitivity and resolution

Unmet Need Mass spectrometry is a method of particle composition analysis. Traditionally, mass spectrometers are large devices with high energy requirements, restricting them to high-resource laboratory settings. Mass spectrometry can be used for isotopic analysis…

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Feature-free photogrammetric 3D imaging with cameras under unconstrained motion

Feature-free photogrammetric 3D imaging with cameras under unconstrained motion

Unmet Need With the increasing development of camera-based sensors for applications such as virtual and augmented reality, there is more demand for technologies that can image 3D structures and create interpretable digital representations – a…

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An automated system for dermatological laser surgery

An automated system for dermatological laser surgery

Value Proposition Laser-based devices show promise for highly effective treatment of a range of cutaneous applications, including skin rejuvenation, tattoo removal, hair removal, vascular and pigmented lesions, and even skin cancers. During these procedures, a…

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Harmonic acoustofluidics for non-contact, dynamic, selective (HANDS) particle manipulation

Harmonic acoustofluidics for non-contact, dynamic, selective (HANDS) particle manipulation

Unmet Need Precise and selective manipulation of microscale particles and cells in liquid suspension (colloidal mixture) is a challenge in the fields of biomedicine and materials science. Current methods for the assembly of colloidal matter…

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Acoustofluidic centrifuge for nanoparticle enrichment and separation

Acoustofluidic centrifuge for nanoparticle enrichment and separation

Unmet Need Nanoparticle manipulation is highly relevant to biomedical and biochemical fields, and the ability to perform nanoparticle concentration and separation has emerged as a critical need in various settings such as point-of-care diagnostics, bioassays,…

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Digital acoustofluidics: contactless liquid handling device via acoustic streaming

Digital acoustofluidics: contactless liquid handling device via acoustic streaming

Value Proposition For decades, scientists have pursued the goal of performing automated reactions in a compact fluid processor with minimal human intervention. Digital microfluidics (DMF) pioneers an appealing solution for economical automation by programmable manipulation…

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Method to trap and transport small particles with acoustic forces

Method to trap and transport small particles with acoustic forces

Value Proposition Acoustic tweezers use ultrasound to create radiation force potential wells that enable precise and contact-free manipulation of physical and biological objects across a broad object size range. It is a fast-developing platform that…

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GOPTICAS: Systems and methods for measurements of Gross Primary Production (GPP)

GOPTICAS: Systems and methods for measurements of Gross Primary Production (GPP)

Unmet Need Over geological timescales, nearly half of the world’s atmospheric oxygen (O2) has been generated in the ocean by marine organisms such as algae, plankton and seaweed. These organisms synthesize oxygen based off the…

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Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach

Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach

Unmet Need High-resolution three-dimensional (3D) imaging techniques have seen widespread adoption as a means by which to develop a real-time map of the world around us, such as is needed by a variety of autonomous…

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Methods to implement three-dimensional (3D) sensing depth cameras

Methods to implement three-dimensional (3D) sensing depth cameras

Unmet Need Real-time high-resolution three-dimensional (3D) imaging is highly desirable in a wide range of fields including biomedical imaging, robotics, virtual/augmented reality, 3D printing, and autonomous vehicles. To accomplish 3D imaging, sensing depth cameras have…

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Pulsating ventilation through a single port

Pulsating ventilation through a single port

Unmet Need Ventilation is a necessity in any enclosed space that requires high air quality and sufficient air flow. Whether for larger spaces, such as buildings, or smaller spaces, such as airplanes, air ventilation provides…

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