Duke OTC Technologies

Agriculture
- Agricultural Engineering
- Crop Improvement
- Food Science & Nutrition
- Other
- Plant Hormones
Antibiotic/anti-viral
Biologics
Biomarkers
By Clinical Application
- Anesthesiology
- Blood & Lymphatic Disease
- CNS & Neurosciences
- Dermatology
- Diabetes, Metabolism, Endocrinology & Obesity
- Ear, Nose, & Throat
- Gastroenterology & Digestive Disease
- General & Plastic Surgery
- Health Education, Medical Training and Operations
- Heart and Vascular
- Immunology, Autoimmune & Inflammation
- Infectious Diseases x
- Mental Health
- Multiple clinical applications
- Musculoskeletal Disorders, Orthopedics/Bone
- Nephrology/Renal
- Oncology
- Ophthalmology
- Orphan Diseases
- Pediatrics
- Physical Medicine & Rehabilitation
- Radiology
- Regenerative Medicine / Tissue Engineering
- Reproductive Health: Obstetrics & Gynecology
- Respiratory & Pulmonary
- Surgery
- Transplantation
- Urology
- Wound Healing
COVID-19
- Diagnostics
- Drug Development
- Masks And Face Shields
- Misc.
- Other Medical Devices
- Vaccines
- Ventilators/Ventilator Parts
Creative Works
Diagnostics
Drug Delivery
Drug screening and discovery
Energy, Cleantech & Environmental
- Air/Water Purification
- Fuel Cells
- Nuclear
- Other
- Renewable Energy
Engineering & Physical Sciences
- Communications & Networking
- Devices & Instrumentation
- Electronics
- Industrial & Manufacturing
- Other
- Photonics
- Semiconductor, MEMS & Nanotechnology
- Transportation & Automotive
Gene therapy
Imaging
- Microscopy
- MRI
- Optical Coherence Tomography
- Other
- Space
- Ultrasound
- X-ray/ CT
Materials
- Biomaterials
- Composites
- Metals
- Other
- Semiconductors
Medical Devices
- Consumable
- Equipment
- Implantable
- Other
- Surgical
Nutraceuticals
Other
Research & Design Tools
- Animal Models
- Antibodies
- Cell Lines
- Human factor/ergonomic design
- Other
- Protein
- Screening assays
- Simulators and modeling tools
- Vectors & Plasmids
RNAi/siRNA
Sensors & Controls
- Biologic
- Non-biological
- Other
Small molecules
Software & Information Technology
- Communications & Networking
- Data Mining
- Databases
- Education & Training
- Healthcare & Bioinformatics
- Human Machine Interface
- Imaging
- Mobile Application
- Open Source
- Other
- Security
- Signal Processing
- Web & Internet
Stem Cells
Vaccines

Probiotic-based prevention of respiratory infections

Unmet Need Pneumonia is the leading infectious killer of children, causing over 800,000 deaths annually. Streptococcus pneumoniae remains a major driver of these fatalities, even with widespread vaccination. Current vaccines are insufficient to address all…

Small molecules that can safely exploit copper as an antimicrobial

Value Proposition The fungal pathogen Cryptococcus neoformans can live in both plants and animals, but when inhaled by humans can disseminate from the lungs to the bloodstream and cause life-threatening systemic disease. The brain is…

SUMOylation as a therapeutic target in inflammatory bowel diseases and sepsis

Unmet Need Inflammatory Bowel Disease (IBD) affects between 2.4 – 3.1 million people in the USA alone, with significant risks of complications such as sepsis. Chronic inflammation from IBD results in severe intestinal tissue damage,…

FK506/FK520 analogs modified to increase fungal specificity and reduce immunosuppression

Unmet Need Fungal infections are becoming increasingly prevalent worldwide, with 150 million cases and 1.7 million fatalities reported in the last year alone. The challenge in treating these infections stems from the rise of multi-drug-resistant…

HIV treatment and prevention using broadly neutralizing antibodies

Unmet Need For over 40 years, the HIV pandemic has affected millions, reducing life expectancy and quality of life. As of 2021, 38.4 million people globally are living with HIV, with about 1.5 million new…

Gene expression signature to predict sepsis mortality

Unmet Need Sepsis is responsible for half of the in-hospital deaths in the US. It is characterized by organ dysfunction resulting from an uncontrolled response to an infection. The standard treatment for sepsis includes source…

Molecular Classifiers of Bacterial Infection

Unmet Need Bacterial infections can lead to various outcomes, with septicemia posing significant morbidity and mortality risks for patients. Septicemia occurs when bacteria enter and spread through the bloodstream, triggering an extreme immune response in…