Duke OTC Technologies

Agriculture
- Agricultural Engineering
- Crop Improvement
- Food Science & Nutrition
- Other
- Plant Hormones
Antibiotic/anti-viral
Biologics
Biomarkers
By Clinical Application
- Anesthesiology
- Blood & Lymphatic Disease
- CNS & Neurosciences
- Dermatology
- Diabetes, Metabolism, Endocrinology & Obesity
- Ear, Nose, & Throat
- Emergency Services
- Gastroenterology & Digestive Disease
- General & Plastic Surgery
- Health Education, Medical Training and Operations
- Heart and Vascular x
- Immunology, Autoimmune & Inflammation
- Infectious Diseases
- Mental Health
- Multiple clinical applications
- Musculoskeletal Disorders, Orthopedics/Bone
- Nephrology/Renal
- Oncology
- Ophthalmology
- Orphan Diseases
- Pediatrics
- Physical Medicine & Rehabilitation
- Radiology
- Regenerative Medicine / Tissue Engineering
- Reproductive Health: Obstetrics & Gynecology
- Respiratory & Pulmonary
- Surgery
- Transplantation
- Urology
- Wound Healing
COVID-19
- Diagnostics
- Drug Development
- Masks And Face Shields
- Misc.
- Other Medical Devices
- Vaccines
- Ventilators/Ventilator Parts
Creative Works
Diagnostics
Drug Delivery
Drug screening and discovery
Energy, Cleantech & Environmental
- Air/Water Purification
- Fuel Cells
- Nuclear
- Other
- Renewable Energy
Engineering & Physical Sciences
- Communications & Networking
- Devices & Instrumentation
- Electronics
- Industrial & Manufacturing
- Other
- Photonics
- Semiconductor, MEMS & Nanotechnology
- Transportation & Automotive
Gene therapy
Imaging
- Microscopy
- MRI
- Optical Coherence Tomography
- Other
- Space
- Ultrasound
- X-ray/ CT
Materials
- Biomaterials
- Composites
- Metals
- Other
- Semiconductors
Medical Devices
- Consumable
- Equipment
- Implantable
- Other
- Surgical
Nutraceuticals
Other
Research & Design Tools ×
- Animal Models
- Antibodies
- Cell Lines
- Human factor/ergonomic design
- Other
- Protein
- Screening assays
- Simulators and modeling tools
- Vectors & Plasmids
RNAi/siRNA
Sensors & Controls
- Biologic
- Non-biological
- Other
Small molecules
Software & Information Technology
- Communications & Networking
- Data Mining
- Databases
- Education & Training
- Healthcare & Bioinformatics
- Human Machine Interface
- Imaging
- Mobile Application
- Open Source
- Other
- Security
- Signal Processing
- Web & Internet
Stem Cells
Vaccines

Novel TRPV4-Targeted Therapy for Arrhythmic Cardiomyopathy

Unmet Need Arrhythmic cardiomyopathy (ACM) is a life-threatening condition characterized by fatty-fibrotic remodeling of the heart muscle, leading to arrhythmias, heart failure, and sudden cardiac death. While 60% of ACM cases are linked to known…

Precision Engineering of Neural Circuits via Designer Connexins for Long-Term Cellular Integration

Unmet Need Gap junctions are crucial for enabling the direct flow of ions and small molecules between cells, playing a significant role in synchronizing electrical activity in organs like the heart and brain. However, mutations…

Transgenic zebrafish to direct epicardial gene expression

Technology Duke inventors have generated a novel zebrafish model that allows researchers to study epicardial cells during embryonic heart development and myocardial regeneration. This zebrafish line is termed Tg(tcf21:CreER)pd42. Specifically, this transgenic model was created…

iPSC line to identify novel therapies for ARVC

Technology Duke inventors have developed a novel induced pluripotent stem cell (iPSC) line that contains a mutation that impacts the TAX1BP3 gene, which causes arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC). Specifically, the iPSCs were derived from…