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Perfusate for optimized gene delivery to donor organs undergoing ex vivo machine perfusion

Perfusate for optimized gene delivery to donor organs undergoing ex vivo machine perfusion

Unmet Need Effective gene delivery is notoriously difficult to achieve to an entire target organ. Gene therapies have traditionally been administered intravascularly, requiring high vector doses to attain therapeutic levels of expression. Because of this…

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Anti-LYPD3 CAR T-cell therapy for the treatment of squamous cell carcinoma

Anti-LYPD3 CAR T-cell therapy for the treatment of squamous cell carcinoma

Unmet Need Chimeric Antigen Receptor (CAR) T-cell therapy, a form of immunotherapy, has proven highly effective against blood cancers such as leukemias and lymphomas. This therapy uses T-cells that are genetically engineering ex vivo to…

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