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Showing 3 matches for the following: Inventor: "Norris, John" ×
A reporter gene C3-T1ba
Reporter Gene used to measure both estrogen and tamoxifen activated estrogen receptor transcriptional activity reconstituted in mammalian cells. Derived from the complement 3 (C3) promotor.
Cell line model of castration resistant prostate cancer
Traditionally, AR drug discovery has used both ligand and AR structure-based design, seeking antagonists by classical ligand binding assays or cellular reporter assays that assess functional antagonism of androgen-dependent transcriptional activation. While these largely empirical…
Cell line model of enzalutamide resistant prostate cancer
Traditionally, AR drug discovery has used both ligand and AR structure-based design, seeking antagonists by classical ligand binding assays or cellular reporter assays that assess functional antagonism of androgen-dependent transcriptional activation. While these largely empirical…