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Making quantitative measurements of intraocular structures with optical coherence tomography

Making quantitative measurements of intraocular structures with optical coherence tomography

Unmet Need Recent advancements in intraoperative optical coherence tomography (OCT) have significantly improved visualization of tool-tissue interactions inside the eye. Visually assisted procedures are becoming effective treatments for previously untreatable genetic or degenerative retinal diseases.…

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A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications

A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications

Unmet Need Diabetic retinopathy (DR) is the leading cause of blindness in working age adults affecting approximately 100 million people worldwide. Studies show that early detection and treatment can reduce the risk of blindness by…

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An optical system to improve glaucoma diagnosis and treatments by monitoring the ocular outflow pathway in vivo

An optical system to improve glaucoma diagnosis and treatments by monitoring the ocular outflow pathway in vivo

Unmet Need Glaucoma, a progressive optic neuropathy, is a leading cause of blindness in this country and the rest of the world. The root cause of primary glaucoma is poorly understood, but risk factors have…

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Performing tissue discrimination for cancer diagnostics using X-ray diffraction imaging

Performing tissue discrimination for cancer diagnostics using X-ray diffraction imaging

Value Proposition Cancer diagnosis is a multi-step process involving a variety of specialties. Radiologists use macroscopic imaging systems to determine where to look for potential cancer, while pathologists use microscopic imaging to confirm cancer at…

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A new method to improve contrast-enhanced MRI by suppressing blood pool signal

A new method to improve contrast-enhanced MRI by suppressing blood pool signal

Unmet Need In magnetic resonance imaging (MRI), contrast agents are often used to enhance the difference between diseased and normal tissue. Images taken with contrast agents allow to identify myocardial infarction, stroke, tumors, atherosclerosis, tissue…

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An algorithm for tracking nutrition that can accurately categorize foods based on image

An algorithm for tracking nutrition that can accurately categorize foods based on image

Unmet Need Obesity prevalence for adults in the United States has reached 42.4% according to the most recent report from the National Center for Health Statistics. Given the public health and medical consequences of obesity…

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Method for fat suppression in T1-weighted inversion recovery MRI

Method for fat suppression in T1-weighted inversion recovery MRI

Unmet Need T1-weighted inversion recovery (IR) imaging is a common MRI technique used for creating a contrast between different types of tissues. This technique allows detecting pathophysiologies in different regions of the body, including the…

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Technique for ghost artifact suppression in MRI imaging

Technique for ghost artifact suppression in MRI imaging

Unmet Need Magnetic Resonance Imaging (MRI) is a safe, non-invasive test that creates detailed images of organs and tissues. In MRI, data is acquired by a scanner running software that sends a sequence of radio…

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Optical device for in vivo assessment of tissues

Optical device for in vivo assessment of tissues

Value Proposition Fluorescence and diffuse reflectance spectroscopy in the ultraviolet-visible (UV-VIS) spectrum are increasingly being investigated for tissue characterization. These biological scatterers, absorbers, and fluorophores may be used to indicate the existence of certain diseases.…

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Method for measuring tissue stiffness using multi-resolution approach to ultrasonic shear wave imaging

Method for measuring tissue stiffness using multi-resolution approach to ultrasonic shear wave imaging

Value Proposition Mechanical properties of biological tissue, such as elasticity, are a strong indicator of the state of tissue health. Accurate assessment of these properties is invaluable for early detection, diagnosis and prognosis of diseases…

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A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue

A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue

Value Proposition Fluorescence spectroscopy has been used successfully to discriminate premalignancy and malignancy in a number of organ sites. However, due to the complex interplay of absorption, scattering, and fluorescence in tissue, it is difficult…

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Integrated parallel reception, excitation, and shimming coil design for magnetic resonance imaging

Integrated parallel reception, excitation, and shimming coil design for magnetic resonance imaging

Unmet Need Magnetic resonance imaging (MRI) is a noninvasive diagnostic tool used by healthcare providers and researchers for a wide range of conditions. MRI is prone to static magnetic field (B0) inhomogeneities induced by the…

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