Skip to main content
Clenbuterol Therapy for Amyotrophic Lateral Sclerosis

Clenbuterol Therapy for Amyotrophic Lateral Sclerosis

Unmet Need Amyotrophic lateral sclerosis (ALS) is a debilitating disease with progressive loss of muscle function and inevitable death usually in 3-5 years. There are currently two available therapies on the market which prolong life…

Read More

A class of biodegradable stealth polymers to improve drug delivery

A class of biodegradable stealth polymers to improve drug delivery

Unmet Need Delivery of drugs or therapeutics such as small molecules, peptides, and proteins, in their native form, is limited by their poor stability, low solubility, and short in vivo circulation. These challenges in drug…

Read More

A method for treating TRAIL-resistant cancers

A method for treating TRAIL-resistant cancers

Unmet Need Over the past twenty years, TNF-related apoptosis-inducing ligand (TRAIL) has been shown to kill a variety of human cancer cells in vitro and in vivo while remaining innocuous to healthy cells. Unfortunately, the…

Read More

An implanted biomaterial to accelerate bone healing

An implanted biomaterial to accelerate bone healing

Unmet Need A leading concept in regenerative medicine is transplantation of tissue-specific cells, often supported with biomaterials, to promote tissue repair. While this strategy has achieved some success, its broad clinical application is hindered by…

Read More

Small molecules that target RNA structures within the CoV genome

Small molecules that target RNA structures within the CoV genome

Unmet Need SARS-CoV-2 is the etiological agent of the COVID-19 respiratory disease, the largest scale respiratory virus pandemic the world has witnessed since the 1918 Spanish flu and that has claimed more than 1.4 million…

Read More

Method for treatment of dementia associated with Alzheimer’s disease and other neurodegenerative diseases

Method for treatment of dementia associated with Alzheimer’s disease and other neurodegenerative diseases

Unmet Need There are over 50 million people worldwide with dementia, with about 10 million new cases diagnosed every year. Though approximately 70% of dementia cases are associated with Alzheimer's disease patients, there is no…

Read More

A tumor-targeting delivery method for chemotherapeutics and other cargo

A tumor-targeting delivery method for chemotherapeutics and other cargo

Unmet Need Delivery and therapeutic efficacy of small molecule imaging agents and chemotherapeutics are hampered by their short half-life, low solubility, non-selectivity to cancer cells, and toxic side effects. Small molecule chemotherapeutics, although in routine…

Read More

Iron-based photosensitizers to replace rare metals in solar energy applications

Iron-based photosensitizers to replace rare metals in solar energy applications

Unmet Need Unlike traditional solar cells composed of crystalline silicone, a new solar technology known as dye-sensitized solar cells (DSSCs), can be manufactured using roll-to-roll printing on transparent and flexible materials, thus providing a low-cost…

Read More

Photo-oxidants with comprehensive visible spectral coverage for energy conversion and catalysis

Photo-oxidants with comprehensive visible spectral coverage for energy conversion and catalysis

Unmet Need Photochemistry, or the use of light to promote chemical reactions, has only recently been adapted by pharmaceutical companies in the past 10 years due to the development of photoredox catalysts that utilize visible…

Read More

A bio-based method for producing adipic acid by using an enzyme to selectively convert 2-oxoadipate to (R)-2-hydroxyadipate

A bio-based method for producing adipic acid by using an enzyme to selectively convert 2-oxoadipate to (R)-2-hydroxyadipate

Unmet Need Adipic acid (1,4-butanedicarboxylic acid; COOH(CH2)4COOH), is among the most-produced chemicals worldwide, with approximately 2.5 billion kilograms synthesized annually and a global market of 8 billion USD. The most typical use for adipic acid…

Read More

Abl kinase inhibitors promote lung regeneration after pathogen and chemical-induced injury

Abl kinase inhibitors promote lung regeneration after pathogen and chemical-induced injury

Value Proposition Damage to the lung epithelium in response to pathogens is a major health problem worldwide. Parenchymal lung infections disrupt lung epithelial architecture and function by eliciting destruction of airway and alveolar cell populations.…

Read More

Targeting drugging molecules that promote cancer metastasis

Targeting drugging molecules that promote cancer metastasis

Value Proposition Metastases, the spread of cancer cells to new areas of the body, are common and devastating complications of many kinds of cancers. For instance, bone metastasis occurs in 73% of advanced breast cancer…

Read More

Have Questions?

Please contact us or subscribe for more opportunities

Stay in Touch with Us