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Wearable device for early detection of influenza and common cold
Unmet Need Approximately 10% of the US population is infected with influenza each year resulting in 3 to 5 million severe cases and up to 500,000 deaths. Early detection of influenza-like illness can limit the…
Novel biosensors made with non-fouling polymer materials
Unmet Need The advancement of personalized medicine and targeted therapies has led to growing interest in high-performance biosensors that detect the presence of target analytes in biological systems. Recently, with the commercial availability of semiconducting…
Portable device for imaging fluorescence microarray chips
Unmet Need Diagnostic assessment of protein biomarkers plays an essential role in modern medical practice, and its availability has a considerable impact on clinical evaluation and decision-making for human health and disease. Fluorescence is the…
A system for screening compounds that alter smell perception
Unmet Need Olfactory sensation profoundly influences a person’s quality of life. In addition to the aesthetic aspects of life associated with olfactory sensation, approximately 2 million Americans experience some type of olfactory dysfunction. Studies show…
A system and method for planning radiosurgery treatments that can better target multiple tumors simultaneously
Unmet Need Brain metastases are the most common neurological complication of primary cancer and are estimated to occur in 9-17% of all cancer patients. Radiosurgery has become a standard treatment technique for brain metastases, which…
A Nano-scintillator fiber optic dosimeter device for accurately measuring radiation during brachytherapy
Value Proposition Two-thirds of all cancer patients receive radiation therapy. However, their radiation dose safety is not currently assured in the clinic. Medically relevant estimations of patient radiation doses received for a specific form of…
A platform for detecting and discriminating odorant molecules in the vapor phase
Unmet Need Mammals are capable of detecting and recognizing a large number of odors. Olfactory receptors (ORs) play a crucial role in detecting and recognizing odorant molecules. There has been growing interest in elucidating the…
Electronic platform for sensing and control of (electro-)chemical reaction
Biological and chemical sensor systems are of great importance in health care, industrial processing, environmental monitoring and remediation, energy production, and national defense. This invention is a sensor and sensing method for controlling surface-based chemical…
Integrated thin film silicon detectors for fluorescence sensing
Unmet Need Microfluidic chip-based systems allow for rapid and sensitive biochemical analyses of very small sample quantities. Due to the prevalence of optical equipment in laboratories, optical detection has become the most popular method for…
Human tracking with coded sensor clusters
A system identifies a human being from the movement of the human being. The system includes a dual element pyroeleetric detector, a Fresnel lens array, and a processor. The dual element pyroelectric detector detects radiation…
Scintillation materials and devices for high-resolution, high-sensitivity, ionizing radiation detectors
Value Proposition Many industries require radiation detection; everything from agriculture to oncology to manufacturing. The proposed Nano-scintillator Fiber Optic Dosimeter (NS-FOD) offers accurate radiation detective in an inexpensive and durable detector. The detector offers a…
A fluorescent probe for monitoring beta-secretase activity in cells
Molecular probes are provided for use in fluorescence microscopy procedures for monitoring beta-secretase enzyme (BACE) activity in living cells and organisms. The probes may be useful for monitoring Alzheimer's Disease-associated BACE in living cells. By…