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Human A1 adrenergic receptor genes
Value Proposition Alpha 1-Adrenergic receptors (alpha 1ARs) are virtually ubiquitous in human tissues and play roles in several important physiological functions such as smooth muscle contraction, glycogenolysis, and myocardial inotropy. Alpha blockers in current clinical…
A plasmid which overproduces the Tet(M) resistance protein (pSH52)
Value Proposition Bacterial resistance to current therapies remains a clinical challenge. For example, numerous enterococcal, staphylococcal, and streptococcal bacterial species are known to exhibit resistance to potent antibacterial tetracycline through upregulation of a ribosomal protection…
A cDNA clone encoding a functional L-proline transporter expressed in rat brain
Value Proposition The L-proline transporter is expressed in several subpopulations of glutamatergic neurons and is implicated in higher cortical functions and memory. Several CNS disorders are associated with L-proline transporter abnormalities, and thus tools for…
An expressible antidepressant-sensitive serotonin transporter
Value Proposition Serotonin-targeting antidepressants are now prescribed for a wide spectrum of disorders, including obsessive-compulsive disorder, depression, as well as eating, sleep, and panic disorders. Next generation therapeutic strategies to combat these disorders, and to…
A cDNA sequence encoding the ATX protein (Human ATX cDNA)
Value Proposition ATX is an active protein kinase that plays a role in cellular stress responses, and defects in ATX also play a role in the development of cancer and other proliferative disorders. Thus, small…