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Showing 2 matches for the following: Inventor: "McDonnell, Donald" ×
Cell line model of castration resistant prostate cancer
Traditionally, AR drug discovery has used both ligand and AR structure-based design, seeking antagonists by classical ligand binding assays or cellular reporter assays that assess functional antagonism of androgen-dependent transcriptional activation. While these largely empirical…
Cell line model of enzalutamide resistant prostate cancer
Traditionally, AR drug discovery has used both ligand and AR structure-based design, seeking antagonists by classical ligand binding assays or cellular reporter assays that assess functional antagonism of androgen-dependent transcriptional activation. While these largely empirical…