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MEAPS: A method to discover bioactive compounds generated by gut microbes
Unmet Need Microbial communities play important roles in environmental, animal, and human health. In humans, beneficial bacteria living within the intestinal tract can promote gut development, balance immunity, and enhance nutrient metabolism. Alternatively, colonization with…
A method of treating and preventing gastrointestinal disorders
Unmet Need Gastrointestinal disorders such as inflammatory bowel disease, constipation, and intestinal pseudo-obstruction have been estimated to affect more than 40% of adults worldwide. These disorders are often associated with alterations in gut microbiota, which…
Novel regulators of root growth
Value Proposition With growing populations and changing climate, agricultural technologies that enhance crop growth and increase stress tolerance are crucial. Stress tolerance, which includes low soil fertility and drought conditions, are relevant to both crop…
Strengthening a patient’s immune functions to prevent infectious diseases without developing antibiotic resistance
Unmet Need Despite the development of numerous antibiotics over the years, the arms race between humans and emergent antibiotic-resistant microbes remains. More than 2.8 million antibiotic-resistant infections and 35,000 deaths occur in the U.S. each…