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Reagentless biosensors to detect multiple analytes
Unmet Need Although biosensors are in widespread use to detect and report analytes, such as the level of nutrients in food and beverage samples, blood glucose in patients, and contamination in water samples, many suffer…
Bio Layer Interferometry Probe (BLIP) for in-vivo analyte detection
Unmet Need Diagnostic tests play a critical role in the clinical diagnosis, management, and monitoring of disease. These tests are designed to analyze biological specimens to identify analytes of interest by employing highly specific and…
A method for end-to-end spatial accuracy quality assurance for radiosurgery
Unmet Need Radiation therapy is an essential element of cancer treatment that benefits 4 million diagnosed patients every year. The ability to deliver complex three-dimensional distributions of dose that conform to even irregularly shaped lesions…
A Nano-scintillator fiber optic dosimeter device for accurately measuring radiation during brachytherapy
Value Proposition Two-thirds of all cancer patients receive radiation therapy. However, their radiation dose safety is not currently assured in the clinic. Medically relevant estimations of patient radiation doses received for a specific form of…
A fluorescent probe for monitoring beta-secretase activity in cells
Molecular probes are provided for use in fluorescence microscopy procedures for monitoring beta-secretase enzyme (BACE) activity in living cells and organisms. The probes may be useful for monitoring Alzheimer's Disease-associated BACE in living cells. By…
Miniaturized, ultra-high density, multichannel electrode array for long-term, intra-cranial neuronal recordings
Technology A high-density multichannel microwire electrode array is disclosed. The array can comprise a variable number of electrodes. A method of assembling the array is further disclosed. Additionally, a plurality of devices employing the array…
Passive pressure sensor
Value proposition Monitoring Intracranial Pressure (ICP) in patients undergoing neurological conditions is critical in tracking progress and recovery. In conditions such as hydrocephalus, a shunt is used to allow extra cerebrospinal fluid to drain. These…
Test of Verbal Expression and Reasoning (TOVER)
The TOVER is non-standardized assessment of expressive language in context and verbal reasoning. The 64 item test was specifically designed to assess language function in children and adults with Down syndrome across a broad range…
Printed biosensors from carbon nanotube thin-film transistors and non-fouling polymer interface layer for label-free, electronic sensing of disease markers in whole blood
Value Proposition The future of diagnostics is in rapid point-of-care detection. The proposed technology is a single-step biosensor that allows for quicker and simpler disease-associated analyte detection. Technology We have developed printed biosensor capable of…