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Surgical device to insert graft between skull and dura
Unmet Need About 16,000 patients per year are diagnosed with a mastoid space defect. This is a defect in the skull that leads to hearing loss caused by cerebrospinal fluid leaking into the mastoid space,…
Tunable elastomer-like polymers for use in soft tissue regeneration and drug delivery
Unmet Need Biodegradable synthetic polymers are often used as scaffolding or support materials in tissue engineering and regenerative medicine. However, many of the materials that have been used widely, such as PLLA and PCL, do…
Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 22.0% predicted to occur until 2024. Medical and dental products account for about…
Engineered conductive polymer for neural activity recording
Unmet Need Dysfunctions in neural circuit activity underlie complex psychiatric diseases such as depression, schizophrenia, Alzheimer’s disease, and others. Neural activity recording is critical to understand brain function and how aberrations in neural circuits lead…
Genetically encoded neuronal electrophysiology
Unmet Need An essential part of studying the brain is understanding how a symphony of neurons activate together, as a circuit, to carry out specific functions. Studying these circuits sheds valuable insight into healthy neurons…
An optical coherence tomography system capable of automatically and accurately imaging eyes without the use of chinrests
Unmet Need Optical coherence tomography (OCT) has revolutionized structural imaging in the eye’s anterior segment and retina. Ophthalmologists now routinely employ OCT in managing ocular diseases, including age-related macular degeneration, diabetic retinopathy, glaucoma, and corneal…
Improved beta oscillation burst detection for assessment of Parkinson’s disease
Unmet Need Parkinson’s disease is a debilitating ailment, though therapies such as deep brain stimulation via electrodes can improve symptoms. Such therapies rely on feedback from biomarkers to adjust the stimulation parameters. Such biomarkers may…
Efficient scan patterns for scanning laser microscopy systems
Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…
Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy
Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…
Surgical drain for fluid collection
Unmet Need Surgical drains are an essential component of various surgical procedures including chest drainage, abdominal surgery, plastic surgery, and neurosurgery. Roughly 4.2 million of these surgeries performed annually in the US require at least…
Stereoscopic heads-up display for displaying surgical data in a Surgical Microscope
Value proposition Typically, microsurgical systems have a console for controlling surgical parameters or visualizing imaging data. In ophthalmic surgeries, the consoles can be used to display Optical Coherence Tomography (OCT) data, which enables great improvements…
Laser surgery targeting and guidance system
Unmet Need Lasers are frequently used in surgery, particularly in dermatology and oncology, to excise harmful tissue from the body. However, due to the difficulties in guiding laser surgical instruments, these tools may fail to…