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Method to optimize spinal cord stimulation therapy placement and parameters

Method to optimize spinal cord stimulation therapy placement and parameters

Unmet Need Spinal cord stimulation (SCS) is an FDA approved therapy that stimulates the spinal cord using electrical pulses. This therapy is used to treat chronic pain, and it is estimated 50,000 spinal cord stimulating…

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A method to optimize neural activity blocking therapies

A method to optimize neural activity blocking therapies

Unmet Need The use of kilohertz frequency (KHF) as neuromodulatory therapies that block unwanted neural activity have been applied to treat chronic pain, phantom limb pain, obesity, and other applications. However, the high energy demands…

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Machine learning algorithm to improve performance of hearing aids and cochlear implants in reverberant environments

Machine learning algorithm to improve performance of hearing aids and cochlear implants in reverberant environments

Unmet Need In the US, nearly 30 million adults require assistive hearing technology such as hearing aids and cochlear implants. Even with assistive devices, hearing impaired individuals have particular trouble with speech recognition in reverberant…

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A method to improve the clinical utility of kilohertz frequency alternating current devices to treat neurological disorders

A method to improve the clinical utility of kilohertz frequency alternating current devices to treat neurological disorders

Unmet Need Many neurological disorders, including pain and spasticity, are characterized by undesirable increases in sensory, motor, or autonomic nerve activity. Local application of kilohertz frequency alternating currents (KHFAC) can effectively and completely block the…

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A focal hypothermia device to slow down tumor growth

A focal hypothermia device to slow down tumor growth

Unmet Need Malignant brain tumors such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG) progress rapidly and can be fatal. Median survival for these cancers is on the order of 15-18 months with…

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An injectable lubricant that is more lubricating with longer in vivo retention than hyaluronic acid

An injectable lubricant that is more lubricating with longer in vivo retention than hyaluronic acid

Unmet Need Hyaluronic acid (HA) is commonly used to treat lubrication deficiencies experienced in eyes, lungs, and other visceral organs. However, the short in vivo residence time of creates a persistent challenge when used as…

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An injectable hydrogel scaffold that delivers gene therapies locally

An injectable hydrogel scaffold that delivers gene therapies locally

Unmet Need Gene therapy has applications ranging from tissue engineering to vaccine development to infectious disease. Most approaches to deliver nucleic material involve the systemic intravenous delivery of condensed nucleic acid (e.g., within a virus…

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A system for securing intraocular lenses during cataract surgery and other applications where sutures create challenges

A system for securing intraocular lenses during cataract surgery and other applications where sutures create challenges

Unmet Need Suturing is a common method to close wounds and fixate devices. However, due to the inherent physical constraints of the intraocular cavity, forming knots within the eye to affix hardware or repair damaged…

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An optimization method for spinal cord stimulation electrodes

An optimization method for spinal cord stimulation electrodes

Unmet Need Spinal cord stimulation is a trusted and proven treatment for patients with chronic pain, and spinal cord stimulator devices are implanted in 34,000 patients a year. Electrical stimulation is delivered via an implanted…

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Method of deep brain stimulation for use in treating Parkinson’s Disease

Method of deep brain stimulation for use in treating Parkinson’s Disease

Value Proposition Parkinson’s disease is a common neurodegenerative disorder that progressively deteriorates the motor system. With over seven million people afflicted globally and a rising incidence rate, improved treatment options for Parkinsonian symptoms will be…

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Model-based optimization of spinal cord stimulation parameters

Model-based optimization of spinal cord stimulation parameters

Value Proposition Spinal cord stimulation (SCS) is an FDA approved therapy for treating chronic lower back and limb pain. SCS is based on the gate control theory of pain, where an implanted pulse generator delivers…

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Passive pressure sensor

Passive pressure sensor

Value proposition Monitoring Intracranial Pressure (ICP) in patients undergoing neurological conditions is critical in tracking progress and recovery. In conditions such as hydrocephalus, a shunt is used to allow extra cerebrospinal fluid to drain. These…

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