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Machine learning algorithm to improve performance of hearing aids and cochlear implants in reverberant environments
Unmet Need In the US, nearly 30 million adults require assistive hearing technology such as hearing aids and cochlear implants. Even with assistive devices, hearing impaired individuals have particular trouble with speech recognition in reverberant…
Central Venous Catheter Insertion Device
Unmet Need Central Venous Catheterization (CVC) is a common procedure where a catheter is inserted into a large vein, typically in the neck, chest, or groin. With 5 million insertions a year, representing 8% of…
Improved beta oscillation burst detection for assessment of Parkinson’s disease
Unmet Need Parkinson’s disease is a debilitating ailment, though therapies such as deep brain stimulation via electrodes can improve symptoms. Such therapies rely on feedback from biomarkers to adjust the stimulation parameters. Such biomarkers may…
Systems and methods for efficient prediction and design of neural stimulation
Unmet Need Bioelectronic therapy is the ability to deliver various electrical impulses to patients through implanted medical devices. These devices can treat heart failure, epilepsy, and chronic pain among other ailments. Depending on the disease,…
Signals for onset-free conduction block
Unmet Need Neuromodulation and neurostimulation devices are used to control the responses of the nervous system and alleviate disease. Delivering to a nerve an alternating current at a high frequency can produce a nerve block…
A drug-infused hydrogel implant for glaucoma drainage devices
Unmet Need Glaucoma is an ocular disease involving heightened eye pressure most commonly leading to blindness, affecting roughly 3 million Americans. Current treatments include anti-steroidal or anti-inflammatory drugs to remove excess ocular fluid or decrease…
Bioresorbable lactone-based elastomers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 21% predicted to occur until 2027. Medical and dental products account for the…
A method for selectively blocking nerve fibers during neurostimulation treatment using kilohertz frequency electrical signals
Unmet Need In the past three decades implanted neurostimulation devices have become widely adopted driven largely by their ability to treat a range of clinical conditions with a “drug-free” solution. The $6.6 billion dollar market…
A method to improve deep brain stimulation treatments by using cortical evoked potentials as a biomarker
Unmet Need Neuromodulation therapies are used to treat a wide variety of clinical conditions. For example, an estimated 150,000 deep brain stimulation (DBS) implants are performed globally to help treat movement disorders like Parkinson’s Disease.…
Tunable elastomer-like polymers for use in soft tissue regeneration and drug delivery
Unmet Need Biodegradable synthetic polymers are often used as scaffolding or support materials in tissue engineering and regenerative medicine. However, many of the materials that have been used widely, such as PLLA and PCL, do…
Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 22.0% predicted to occur until 2024. Medical and dental products account for about…
A method to optimize neural activity blocking therapies
Unmet Need The use of kilohertz frequency (KHF) as neuromodulatory therapies that block unwanted neural activity have been applied to treat chronic pain, phantom limb pain, obesity, and other applications. However, the high energy demands…