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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones
Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…
3D Sensing System with Automated Data Output for Objective Cervical Dystonia Diagnosis and Treatment Monitoring
Unmet Need Cervical dystonia is a neurological disorder affecting about 60,000 people in the United States, characterized by abnormal postures, tremor, pain, and spasms of the neck muscles. Current measurements of cervical dystonia rely on…
A smartphone-based detector for mobile health applications
Unmet Need It is estimated that there are over 6 billion smartphone users worldwide, which translates to almost 83% of the world’s population. Due to their widespread use, smartphones present a golden opportunity to redefine…
Efficient scan patterns for scanning laser microscopy systems
Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…
Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy
Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…
Laser surgery targeting and guidance system
Unmet Need Lasers are frequently used in surgery, particularly in dermatology and oncology, to excise harmful tissue from the body. However, due to the difficulties in guiding laser surgical instruments, these tools may fail to…
Smart microscope for diagnosing disease
Value Proposition Since its invention, the microscope has been optimized for interpretation by a human observer. Recently, however, deep learning algorithms have been developed for automated image analysis in a variety of important contexts, such…
A high-speed echocardiographic system that can assess cardiac function in real-time
Unmet Need Since its inception in the mid-1970s, real-time echocardiography employing phased array principles has had a significant impact on the practice of medicine particularly in cardiology. The real-time or live nature of image formation…
Making quantitative measurements of intraocular structures with optical coherence tomography
Unmet Need Recent advancements in intraoperative optical coherence tomography (OCT) have significantly improved visualization of tool-tissue interactions inside the eye. Visually assisted procedures are becoming effective treatments for previously untreatable genetic or degenerative retinal diseases.…
A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications
Unmet Need Diabetic retinopathy (DR) is the leading cause of blindness in working age adults affecting approximately 100 million people worldwide. Studies show that early detection and treatment can reduce the risk of blindness by…
Drug diversion surveillance dashboard
Value Proposition Prescription drug diversion is defined as the illegal distribution or misuse of prescription medications. Drugs that are susceptible to abuse and addiction in at-risk individuals are commonly involved. In the light of nationwide…