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Viral-mediated humanized mouse model for Parkinson’s disease
Unmet Need Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the midbrain and the accumulation of α-synuclein aggregates (Lewy bodies), leading to motor and cognitive impairments. PD…
Method to improve durability of polymer networks of crosslinked elastomers
Unmet Need The lifespan of polymer materials is limited by premature failure due to poor mechanical properties such as toughness. Increased polymer toughness enhances material performance by improving its ability to absorb stress before breaking,…
Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 22.0% predicted to occur until 2024. Medical and dental products account for about…
Photo-oxidants with comprehensive visible spectral coverage for energy conversion and catalysis
Unmet Need Photochemistry, or the use of light to promote chemical reactions, has only recently been adapted by pharmaceutical companies in the past 10 years due to the development of photoredox catalysts that utilize visible…
Nano-Scintillator Fiber Optic Dosimeter for Real-Time Radiation Detection
Unmet Need There is a need for accurate, real-time radiation detection across various industries, including healthcare, security, and manufacturing. Current scintillator-based detectors often suffer from limitations such as large spatial requirements, reliance on cryogenic cooling,…
Advanced adaptive cooling fabric
Unmet Need With the rise of temperatures due to global warming, the risk of heat-related illnesses such as heat exhaustion and heatstroke is on the rise as well. Some of the most vulnerable are those…
A rapid and low-cost method for benchtop microfabrication of thermoplastic microdevices using UV light and miniaturization
Unmet Need Microfluidics has shown considerable promise for advancing biomedical research and improving diagnostics. Various methods for fabricating channels for microfluidic devices have been developed. However, the majority of micropatterning techniques are costly, time-consuming, and…
Transparent silver nanowire composite film and method of application for flexible touch screens
Unmet Need Current flexible touch screens employ complex haptic feedback for user perception and nanowire mesh materials that have high fog leading to decreased visual acuity. With a flexible display market expected to reach $65.3…
Bioresorbable lactone-based elastomers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 21% predicted to occur until 2027. Medical and dental products account for the…
Sugar-based polymers with easily tuned mechanical properties that range from plastic to elastomeric
Unmet Need The production of plastics from renewable sources is one of the fastest-growing materials sectors. Bioplastics offer an alternative to the use of petroleum as a feedstock, which suffers from a variety of disadvantages…
A method to increase the durability and lifespan of commercially available soft polymer networks
Unmet Need Soft polymers are used for a variety of products including biomedical implants, footwear, and tires. Having a more durable polymer product will increase not only the lifespan of the product but also the…
Method to produce durable synthetic rubbers that exhibit strain-induced crystallization (SIC) at ambient temperature
Unmet Need Polybutadiene is a synthetic rubber with high elasticity, resistance to wear, and robust ability to return to its original shape following deformation. These desirable characteristics have led to widespread use within manufacturing, namely…