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Bioresorbable lactone-based elastomers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 21% predicted to occur until 2027. Medical and dental products account for the…
A synergistic chemotherapy and radiotherapy drug delivery technology for treating prostate cancer tumors
Unmet Need Pancreatic cancer is one of the deadliest manifestations of cancer in clinical oncology. Despite accounting for only 3.2% of all cancer cases, it is the third leading cause of cancer-related mortality. National Comprehensive…
Tunable elastomer-like polymers for use in soft tissue regeneration and drug delivery
Unmet Need Biodegradable synthetic polymers are often used as scaffolding or support materials in tissue engineering and regenerative medicine. However, many of the materials that have been used widely, such as PLLA and PCL, do…
Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 22.0% predicted to occur until 2024. Medical and dental products account for about…
Biomaterial therapy for healing brain tissue after ischemic stroke
Unmet Need Ischemic stroke affects 692,000 patients annually in the United States, and can result in paralysis and complications related to cognition and motor function. After a stroke, scarring and atrophy can occur at the…
Biomaterial pouch for long-term xenogeneic cell transplantation
Unmet Need Cell therapy is an exciting therapeutic approach that is growing rapidly – there are more than 1,000 cell therapy clinical trials that are currently active in many different fields like oncology, neurology, hematology,…
Enzymatic synthesis of aptamer-targeted polynucleotide drug delivery platforms for cancer therapy
Unmet Need In the United States alone, over 1.8 million new patients were diagnosed with cancer in 2021, and over 600,000 patients died from the disease. Cytostatic nucleotides, such as gemcitabine and 5-fluorouracil, have been…
Sugar-based polymers with easily tuned mechanical properties that range from plastic to elastomeric
Unmet Need The production of plastics from renewable sources is one of the fastest-growing materials sectors. Bioplastics offer an alternative to the use of petroleum as a feedstock, which suffers from a variety of disadvantages…
A green and efficient free radical initiator system for producing hydrogels
Unmet Need Hydrogels are heavily employed in agriculture, commercial wound dressings, and hygienic products, with more recent development in biomedical applications, including drug delivery, bioelectronics, bioimaging, and tissue engineering. Free radical polymerization is one of…
Novel biosensors made with non-fouling polymer materials
Unmet Need The advancement of personalized medicine and targeted therapies has led to growing interest in high-performance biosensors that detect the presence of target analytes in biological systems. Recently, with the commercial availability of semiconducting…
An injectable lubricant that is more lubricating with longer in vivo retention than hyaluronic acid
Unmet Need Hyaluronic acid (HA) is commonly used to treat lubrication deficiencies experienced in eyes, lungs, and other visceral organs. However, the short in vivo residence time of creates a persistent challenge when used as…
A class of biodegradable stealth polymers to improve drug delivery
Unmet Need Delivery of drugs or therapeutics such as small molecules, peptides, and proteins, in their native form, is limited by their poor stability, low solubility, and short in vivo circulation. These challenges in drug…