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A microscopy method for acquiring polarization-sensitive phase information in 3D
Unmet Need The majority of biological research and clinical diagnostics has involved the use of optical imaging systems for transparent specimens that rely on scalar properties like phase contrast. These systems have proved useful for…
Multiscale coherence imaging for assessing epithelial tissue health in precancerous detection
Unmet Need Epithelial cells act as the body’s first line of defense against foreign elements and are constantly being replaced by newly grown cells. Due in part to these factors, 90% of all cancers originate…
Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy
Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…
Efficient scan patterns for scanning laser microscopy systems
Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…
Stereoscopic heads-up display for displaying surgical data in a Surgical Microscope
Value proposition Typically, microsurgical systems have a console for controlling surgical parameters or visualizing imaging data. In ophthalmic surgeries, the consoles can be used to display Optical Coherence Tomography (OCT) data, which enables great improvements…
A robotic system for ultrasound-guided vein localization
Unmet Need Robotic instruments are increasingly used in medical care, with robot-controlled surgical and radiological tools becoming increasingly common across a range of specialties. However, certain specialties have not yet benefited from advances in medical…
Smart microscope for diagnosing disease
Value Proposition Since its invention, the microscope has been optimized for interpretation by a human observer. Recently, however, deep learning algorithms have been developed for automated image analysis in a variety of important contexts, such…
Micromachined transducer arrays for improved ultrasound imaging
Unmet Need With the surge of minimally invasive surgeries comes the demand of improved imaging techniques to assist in obtaining successful outcomes. Intravascular (catheter-based) ultrasound has emerged as a leading imaging technology for minimally invasive…
A quality control tool for multi-energy X-ray computed tomography imaging
Unmet Need X-ray computed tomography (CT) imaging devices are ubiquitous in any radiology department and CT examinations are among the most commonly ordered diagnostic procedure. Multi-energy computed tomography is an emerging imaging technology that is…
Novel system for improved aiming during optical coherence tomography imaging of young children
Unmet Need When a retinal condition is suspected in a patient, optical coherence tomography (OCT) is used to obtain detailed images of the retina. Due to the large amount of data needed to be processed…
A method to eliminate beam hardening artifacts and to improve CT quantitative imaging ability
Unmet Need For many commercially available CT scanners, the photons emitted from the X-ray source spread within a wide and continuous distribution of energy spectrum. As the poly-energetic X-ray beam passes through matter like tissue,…
A high-speed echocardiographic system that can assess cardiac function in real-time
Unmet Need Since its inception in the mid-1970s, real-time echocardiography employing phased array principles has had a significant impact on the practice of medicine particularly in cardiology. The real-time or live nature of image formation…