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High-speed 3D tomographic imaging using a camera array
Unmet Need Tomographic imaging has revolutionized both scientific research and clinical procedures. 3D tomographic imaging reveals information about a sample’s volume, depth, and internal structures, which cannot be obtained from 2D imaging alone. However, 3D…
Auto-aligning slit lamp for eye exams
Unmet Need At least 2.2 billion people in the world have vision impairment. In 2019, there were 60 million incident cases and 438.4 thousand years lived with disability of eye injury. Almost half of these…
Auto-aligning handheld optical coherence tomography probe
Unmet Need Optical coherence tomography (OCT) is an optical imaging modality that uses low-coherence light to non-invasively obtain high resolution ocular images of structures including the retina and optic nerve. OCT has advantages over other…
Nano-Scintillator Fiber Optic Dosimeter for Real-Time Radiation Detection
Unmet Need There is a need for accurate, real-time radiation detection across various industries, including healthcare, security, and manufacturing. Current scintillator-based detectors often suffer from limitations such as large spatial requirements, reliance on cryogenic cooling,…
Depth-Resolved Spectroscopic Imaging System for Early Cancer Detection and Diagnosis
Unmet Need Colorectal and esophageal cancers rank among the leading causes of cancer deaths in the United States. Early detection through screening is key to reducing mortality rates. Current screening methods, like colonoscopy for colorectal…
3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones
Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…
Feature-free photogrammetric 3D imaging with cameras under unconstrained motion
Unmet Need With the increasing development of camera-based sensors for applications such as virtual and augmented reality, there is more demand for technologies that can image 3D structures and create interpretable digital representations – a…
Dark-Blood Delayed-Enhancement MRI: Improved Tissue Contrast and Blood-Pool Signal Suppression
Unmet Need Delayed-enhancement MRI (DE-MRI) is the standard for imaging myocardial infarction (MI), providing high-resolution maps of infarcted and viable myocardium. However, DE-MRI often suffers from poor differentiation between infarcted myocardium and the bright left…
MRI method for detecting partial fatty tissue infiltration within the body
Unmet Need Through magnetic resonance imaging (MRI), it is possible to image and differentiate tissues and biological elements throughout the body. However, due to some tissues of the body having similar chemical compositions and subsequent…
Vectorial Fourier ptychography for high-resolution widefield polarization imaging in pathology and research
Unmet Need In the United States, over 10,000 diagnostic imaging centers rely on microscopy for diagnostics, with 70-80% of healthcare decisions dependent on timely pathology-based tests, a demand that is expected to grow. Fourier ptychography…
Advanced remote monitoring and prediction of deep-seated landslide risk using SAR and physical modeling
Unmet Need Deep-seated landslides are some of the most catastrophic natural hazards, gradually moving almost imperceptibly over many years before suddenly collapsing in a dramatic fashion. Conventional prediction methods depend on physical access through boreholes,…
Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach
Unmet Need High-resolution three-dimensional (3D) imaging techniques have seen widespread adoption as a means by which to develop a real-time map of the world around us, such as is needed by a variety of autonomous…