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Techniques for the segmentation of layered structures using graph theory and dynamic programming
Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges.…
Long working distance optical coherence tomography system
Value Proposition Optical coherence tomography (OCT) has become the standard of care for diagnosis of many retinal pathologies. However, current commercial OCT systems require a skilled technician/photographer and cooperative subjects to obtain and maintain subject…
Automated segmentation of layered structures such as retinal layers using graph cuts
Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges.…
Black blood delayed enhancement magnetic resonance imaging
Technnology Duke University is seeking a corporate partners to commercialize a method of improved detection of infarcted heart tissue. The technology provides a dark blood delayed enhancement technique that improves the visualization of subendocardial infarcts…
Systems and methods for ophthalmic surgical microscope mounted optical coherence tomography
Value Proposition Surgical visualization has changed drastically since its inception, incorporating larger, more advanced optics toward increasing illumination and field-of-view (FOV). However, the limiting factor in vitreoretinal surgery remains the ability to distinguish between tissues…
Real-time optical coherence tomography processing software
Value Proposition Optical coherence tomography (OCT) has revolutionized retinal diagnostics and is rapidly expanding into surgical settings. Currently, surgical OCT systems are limited to visualization of 2D images of live surgery. This resulted in difficulties…
Providing surface contrast in rendering of three-dimensional images for micro-surgical applications
Value Proposition Recent advancements in optical coherence tomography (OCT) technology have greatly improved image quality and have facilitated the acquisition, processing, and display of three-dimensional information in real-time. As a result, this technology can now…
Pupil tracking for motion corrected ophthalmic optical coherence tomography
Value proposition Optical Coherence Tomography (OCT) is the standard of care used in diagnosis as well as following the treatment of several pathological ophthalmic conditions. Volumetric acquisition with anterior segment optical coherence tomography (ASOCT) is…
Structured illumination super-resolution phase microscopy
Value Proposition Many biologically relevant samples, such as live cells or micro-organisms, are transparent under visible illumination, and thus do not scatter or absorb light significantly. Thus, normal intensity imaging modalities, such as typical light…
RNA aptamers for thrombi imaging
Value Proposition Thrombosis (blood clots within blood vessels) is a major underlying factor in many cardiovascular diseases and a major source for complications following hospital stays and surgeries. Venous thrombosis occurs in approximately 1 per…
Optimization of fiber optic probes for spectroscopic measurements
Value Proposition Early detection of cancer greatly increases the chances for a positive outcome. The World Health Organization states that there are two major components of early detection of cancer: increased awareness and screening. Diffuse…
Compact telescope design for light scanning systems
Value Proposition Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) are retinal imaging modalities commonly utilized in the clinic to diagnose retinal diseases. SLO is a confocal imaging technique similar to confocal microscopy that…