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Predicting progression of osteoarthritis by feature analysis of bone radiographs
Unmet Need Osteoarthritis (OA) is a leading cause of disability among adults, it currently affects more than 27 million Americans and more than 300 million individuals worldwide. Currently, there are no validated predictors of OA…
Adaptive ultrasound frequency selection
Unmet Need Acoustic clutter is a phenomenon that contributes to poor quality ultrasound images. It often manifests as haze with grainy patterns that overlay the true ultrasound image and reduces the conspicuity of targets by…
A method for end-to-end spatial accuracy quality assurance for radiosurgery
Unmet Need Radiation therapy is an essential element of cancer treatment that benefits 4 million diagnosed patients every year. The ability to deliver complex three-dimensional distributions of dose that conform to even irregularly shaped lesions…
A method for validating complex radiation treatments using 3D dosimetry that can be implemented remotely
Unmet Need Radiation therapy is an essential element of cancer treatment that has been estimated to be potentially beneficial to 4 million diagnosed patients every year. The advent of commercially available magnetic resonance imaging guided…
An optical scanning system that reduces the planning cost associated with 3D dosimetry planning techniques
Unmet Need Radiation therapy is an essential element of cancer treatment that has been estimated to be potentially beneficial to 4 million diagnosed patients every year. Since the turn of the millennium, the sophistication, precision,…
Dynamic MRI of lungs using perfluorinated gas mixtures
Unmet Need Chronic obstructive pulmonary disease (COPD) is the 3d leading cause of death in the US. It has consistently increased in frequency over the past 4 decades, currently including 15-20 million diagnosed cases. COPD…
MRI image processing using virtual frequency-selective inversion
Unmet Need In magnetic resonance imaging (MRI), data is acquired by a scanner that sends a sequence of radio frequency (RF) pulses into the tissue placed in a strong magnetic field. The magnetic field causes…
Making quantitative measurements of intraocular structures with optical coherence tomography
Unmet Need Recent advancements in intraoperative optical coherence tomography (OCT) have significantly improved visualization of tool-tissue interactions inside the eye. Visually assisted procedures are becoming effective treatments for previously untreatable genetic or degenerative retinal diseases.…
A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications
Unmet Need Diabetic retinopathy (DR) is the leading cause of blindness in working age adults affecting approximately 100 million people worldwide. Studies show that early detection and treatment can reduce the risk of blindness by…
An optical system to improve glaucoma diagnosis and treatments by monitoring the ocular outflow pathway in vivo
Unmet Need Glaucoma, a progressive optic neuropathy, is a leading cause of blindness in this country and the rest of the world. The root cause of primary glaucoma is poorly understood, but risk factors have…
Performing tissue discrimination for cancer diagnostics using X-ray diffraction imaging
Value Proposition Cancer diagnosis is a multi-step process involving a variety of specialties. Radiologists use macroscopic imaging systems to determine where to look for potential cancer, while pathologists use microscopic imaging to confirm cancer at…
A method for reducing speckle and improving resolution in ultrasound imaging
Value Proposition For many years, ultrasound imaging has been an important and popular medical imaging method. The speckle texture in ultrasound images limits the detectability of low contrast targets. With size on the order of…