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System for detecting three protein-protein interactions in living cells
Unmet Need Recognizing Protein-Protein Interactions (PPIs) is central to many molecular biology studies aiming to identify important targets for the development of therapeutic drugs. There are thousands of PPIs that are essential to understand the…
Acoustic imaging with metamaterial Luneburg lenses
Unmet Need Controlling and focusing acoustic waves is a crucial component of fields such as ultrasonic sensing and speaker system design. Luneburg lenses, spherically symmetrical gradient refractive index (GRIN) devices with unique imaging properties, are…
Acoustic lensing and holographic reconstruction with metamaterials
Unmet Need Manipulation of sound waves in air often requires many amps, transducers, and the electronics to control them, making applications like ultrasonic sensors for cars and wireless power transfer complex and power intensive. Acoustic…
Memory-efficient deep learning algorithms for computed tomography image reconstruction
Unmet Need Using high resolution images such as computed tomography (CT) has become a popular tool to guide medical interventions from radiotherapy to dental implantation. The market for CT services is expected to grow from…
A quality control tool for multi-energy X-ray computed tomography imaging
Unmet Need X-ray computed tomography (CT) imaging devices are ubiquitous in any radiology department and CT examinations are among the most commonly ordered diagnostic procedure. Multi-energy computed tomography is an emerging imaging technology that is…
Novel system for improved aiming during optical coherence tomography imaging of young children
Unmet Need When a retinal condition is suspected in a patient, optical coherence tomography (OCT) is used to obtain detailed images of the retina. Due to the large amount of data needed to be processed…
Method for rapid coil placement and E-field evaluation during TMS
Unmet Need Transcranial magnetic stimulation (TMS) is a noninvasive brain stimulation technique where a TMS coil placed on the scalp is used to induce a high intensity electric field (E-field) that directly modulates the activity…
Systems and methods to noninvasively enhance the visual acuity for patients with retinal prostheses
Unmet Need Degenerative eye diseases lead to a profound decrease in quality of life, and their incidence is on the rise. In high- and middle-income countries, age-related macular degeneration is the main and growing cause…
A method to eliminate beam hardening artifacts and to improve CT quantitative imaging ability
Unmet Need For many commercially available CT scanners, the photons emitted from the X-ray source spread within a wide and continuous distribution of energy spectrum. As the poly-energetic X-ray beam passes through matter like tissue,…
Virtual frequency-selective inversion method for fat suppression in MRI
Unmet Need In magnetic resonance imaging (MRI), data is acquired by a scanner that sends a sequence of radio frequency (RF) pulses into the tissue placed in a strong magnetic field. The magnetic field causes…
A high-speed echocardiographic system that can assess cardiac function in real-time
Unmet Need Since its inception in the mid-1970s, real-time echocardiography employing phased array principles has had a significant impact on the practice of medicine particularly in cardiology. The real-time or live nature of image formation…
Portable device for imaging fluorescence microarray chips
Unmet Need Diagnostic assessment of protein biomarkers plays an essential role in modern medical practice, and its availability has a considerable impact on clinical evaluation and decision-making for human health and disease. Fluorescence is the…