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An optical coherence tomography system capable of automatically and accurately imaging eyes without the use of chinrests

An optical coherence tomography system capable of automatically and accurately imaging eyes without the use of chinrests

Unmet Need Optical coherence tomography (OCT) has revolutionized structural imaging in the eye’s anterior segment and retina. Ophthalmologists now routinely employ OCT in managing ocular diseases, including age-related macular degeneration, diabetic retinopathy, glaucoma, and corneal…

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Computational methods to introduce image contrast from multidimensional data

Computational methods to introduce image contrast from multidimensional data

Unmet Need Three-dimensional (3D) imaging techniques, such as optical coherence tomography (OCT), have been successfully used as an in vivo diagnostic modality for a wide range of clinical areas including ophthalmology, cardiology, and gastroenterology. For…

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Automatic segmentation software to diagnose retinopathy of prematurity (ROP) from optical coherence tomography images in preterm infants

Automatic segmentation software to diagnose retinopathy of prematurity (ROP) from optical coherence tomography images in preterm infants

Unmet Need Retinopathy of prematurity (ROP) is a developmental vascular proliferative disorder that occurs in approximately 50-70% of preterm infants and is a leading cause of childhood blindness. The most critical factor in identifying ROP…

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Methods to implement three-dimensional (3D) sensing depth cameras

Methods to implement three-dimensional (3D) sensing depth cameras

Unmet Need Real-time high-resolution three-dimensional (3D) imaging is highly desirable in a wide range of fields including biomedical imaging, robotics, virtual/augmented reality, 3D printing, and autonomous vehicles. To accomplish 3D imaging, sensing depth cameras have…

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Efficient scan patterns for scanning laser microscopy systems

Efficient scan patterns for scanning laser microscopy systems

Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…

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Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy

Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy

Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…

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Making quantitative measurements of intraocular structures with optical coherence tomography

Making quantitative measurements of intraocular structures with optical coherence tomography

Unmet Need Recent advancements in intraoperative optical coherence tomography (OCT) have significantly improved visualization of tool-tissue interactions inside the eye. Visually assisted procedures are becoming effective treatments for previously untreatable genetic or degenerative retinal diseases.…

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A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications

A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications

Unmet Need Diabetic retinopathy (DR) is the leading cause of blindness in working age adults affecting approximately 100 million people worldwide. Studies show that early detection and treatment can reduce the risk of blindness by…

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Providing surface contrast in rendering of three-dimensional images for micro-surgical applications

Providing surface contrast in rendering of three-dimensional images for micro-surgical applications

Value Proposition Recent advancements in optical coherence tomography (OCT) technology have greatly improved image quality and have facilitated the acquisition, processing, and display of three-dimensional information in real-time. As a result, this technology can now…

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Real-time optical coherence tomography processing software

Real-time optical coherence tomography processing software

Value Proposition Optical coherence tomography (OCT) has revolutionized retinal diagnostics and is rapidly expanding into surgical settings. Currently, surgical OCT systems are limited to visualization of 2D images of live surgery. This resulted in difficulties…

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