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Methods and compositions to sense m6A RNA modifications using a genetically encoded sensor

Methods and compositions to sense m6A RNA modifications using a genetically encoded sensor

Unmet Need Gene expression is highly regulated through the addition of chemical modifications to RNA molecules. One such modification is methylation of adenosine residues to form m6A, a modified nucleotide which is found in thousands…

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Breast cancer risk prediction technology using genomic classifier

Breast cancer risk prediction technology using genomic classifier

Unmet Need The earliest form of breast cancer, ductal carcinoma in situ (DCIS), is diagnosed in almost 50,000 people in the U.S. each year. DCIS is considered noninvasive, as abnormal cells have not spread out…

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A method for identifying sour-taste receptor ligands as well as compounds that modulate their activity

A method for identifying sour-taste receptor ligands as well as compounds that modulate their activity

Unmet Need The taste system is essential for feeding and survival as it helps humans evaluate the nutritional content in food. Every year, taste and smell dysfunctions affect more than 200,000 people, including those undergoing…

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Rapid immunoassay to detect anti-EGFRviii levels to evaluate vaccine efficacy

Rapid immunoassay to detect anti-EGFRviii levels to evaluate vaccine efficacy

Value Proposition Tumor-specific molecules offer the possibility of targeted cancer therapy using monoclonal antibodies (mAbs) specifically directed against the tumor-specific molecule. However, it has proven difficult to identify tumor-specific molecules. Overexpression of EGFR in human…

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