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Reagentless biosensors to detect multiple analytes
Unmet Need Although biosensors are in widespread use to detect and report analytes, such as the level of nutrients in food and beverage samples, blood glucose in patients, and contamination in water samples, many suffer…
A smartphone-based detector for mobile health applications
Unmet Need It is estimated that there are over 6 billion smartphone users worldwide, which translates to almost 83% of the world’s population. Due to their widespread use, smartphones present a golden opportunity to redefine…
Bio Layer Interferometry Probe (BLIP) for in-vivo analyte detection
Unmet Need Diagnostic tests play a critical role in the clinical diagnosis, management, and monitoring of disease. These tests are designed to analyze biological specimens to identify analytes of interest by employing highly specific and…
Method to trap and transport small particles with acoustic forces
Value Proposition Acoustic tweezers use ultrasound to create radiation force potential wells that enable precise and contact-free manipulation of physical and biological objects across a broad object size range. It is a fast-developing platform that…
A quality control tool for multi-energy X-ray computed tomography imaging
Unmet Need X-ray computed tomography (CT) imaging devices are ubiquitous in any radiology department and CT examinations are among the most commonly ordered diagnostic procedure. Multi-energy computed tomography is an emerging imaging technology that is…
Fiber optic probes with self-calibration capability for tissue optical spectroscopy
Value Proposition UV-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) is sensitive to the absorption and scattering properties of biological molecules in tissue and thus can be used as a noninvasive in vivo tool to obtain quantitative…
TARGET: Tunable and Amplified Raman Gold Nanoprobes for Effective Tracking
Unmet Need Surface-enhanced Raman scattering (SERS) has led to the development of important biomedical analysis and sensing tools ranging from in vitro diagnostics to in vivo imaging through SERS nanoprobes. However, these nanoprobes have limited…
A method for detecting RNA and DNA using surface-enhanced Raman scattering (SERS)
Unmet Need The development of practical and sensitive techniques for screening nucleic acid biomarkers related to medical diseases and cancers is critical for early diagnosis, prevention, and effective interventions. Recent advances in molecular profiling technology…
Endoscopic optical assessment of tissue histology
Value Proposition Endoscopy is an extremely important and prevalent procedure for the diagnosis of a variety of disorders affecting the esophageal and gastrointestinal tracts such as colorectal cancer, adenoma, inflammatory bowel disease, and intestinal metaplasia.…
Printed biosensors from carbon nanotube thin-film transistors and non-fouling polymer interface layer for label-free, electronic sensing of disease markers in whole blood
Value Proposition The future of diagnostics is in rapid point-of-care detection. The proposed technology is a single-step biosensor that allows for quicker and simpler disease-associated analyte detection. Technology We have developed printed biosensor capable of…