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Multiscale coherence imaging for assessing epithelial tissue health in precancerous detection

Multiscale coherence imaging for assessing epithelial tissue health in precancerous detection

Unmet Need Epithelial cells act as the body’s first line of defense against foreign elements and are constantly being replaced by newly grown cells. Due in part to these factors, 90% of all cancers originate…

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Connecting cardiac and respiratory 3DCT imaging for 5DCT heart motion management

Connecting cardiac and respiratory 3DCT imaging for 5DCT heart motion management

Unmet Need Ventricular tachycardia (VT) is a primary condition of heart disease noted as an irregularity of heart rhythm due to improper electrical signaling in the ventricles that causes an abnormally high heart rate. VT…

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All dielectric absorber for improved real-time imaging in the terahertz spectrum

All dielectric absorber for improved real-time imaging in the terahertz spectrum

Value Proposition Discoveries over the past decades have unveiled unique characteristics of the far-infrared or terahertz (THz) spectrum spanning from 0.3 THz to 10 THz, including non-ionization of biological materials, easy penetration into dielectric and…

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A quality control tool for multi-energy X-ray computed tomography imaging

A quality control tool for multi-energy X-ray computed tomography imaging

Unmet Need X-ray computed tomography (CT) imaging devices are ubiquitous in any radiology department and CT examinations are among the most commonly ordered diagnostic procedure. Multi-energy computed tomography is an emerging imaging technology that is…

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Optical device for in vivo assessment of tissues

Optical device for in vivo assessment of tissues

Value Proposition Fluorescence and diffuse reflectance spectroscopy in the ultraviolet-visible (UV-VIS) spectrum are increasingly being investigated for tissue characterization. These biological scatterers, absorbers, and fluorophores may be used to indicate the existence of certain diseases.…

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A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue

A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue

Value Proposition Fluorescence spectroscopy has been used successfully to discriminate premalignancy and malignancy in a number of organ sites. However, due to the complex interplay of absorption, scattering, and fluorescence in tissue, it is difficult…

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Fiber optic probes with self-calibration capability for tissue optical spectroscopy

Fiber optic probes with self-calibration capability for tissue optical spectroscopy

Value Proposition UV-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) is sensitive to the absorption and scattering properties of biological molecules in tissue and thus can be used as a noninvasive in vivo tool to obtain quantitative…

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TARGET: Tunable and Amplified Raman Gold Nanoprobes for Effective Tracking

TARGET: Tunable and Amplified Raman Gold Nanoprobes for Effective Tracking

Unmet Need Surface-enhanced Raman scattering (SERS) has led to the development of important biomedical analysis and sensing tools ranging from in vitro diagnostics to in vivo imaging through SERS nanoprobes. However, these nanoprobes have limited…

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Black blood delayed enhancement magnetic resonance imaging

Black blood delayed enhancement magnetic resonance imaging

Technnology Duke University is seeking a corporate partners to commercialize a method of improved detection of infarcted heart tissue. The technology provides a dark blood delayed enhancement technique that improves the visualization of subendocardial infarcts…

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