You searched for — Duke OTC

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Prognostic and predictive blood-based biomarkers for pancreatic cancer

Value Proposition Pancreatic cancer is among the deadliest types of cancer, with only 8.2% of patients surviving five years after diagnosis. Therapeutics that inhibit either VEGF signaling pathways or mitogenic signaling through the epidermal growth…

Rapid immunoassay to detect anti-EGFRviii levels to evaluate vaccine efficacy

Value Proposition Tumor-specific molecules offer the possibility of targeted cancer therapy using monoclonal antibodies (mAbs) specifically directed against the tumor-specific molecule. However, it has proven difficult to identify tumor-specific molecules. Overexpression of EGFR in human…

Components of the Wnt-Beta-catenin paracrine signaling pathway as predictive biomarkers for cancer immunotherapy

Value Proposition Immunotherapy is a promising approach for the treatment of many cancers. However, despite early success, majority of patients with advanced cancer fail to respond or become resistant. In even the most immunogenic cancer…

Endoscopic optical assessment of tissue histology

Value Proposition Endoscopy is an extremely important and prevalent procedure for the diagnosis of a variety of disorders affecting the esophageal and gastrointestinal tracts such as colorectal cancer, adenoma, inflammatory bowel disease, and intestinal metaplasia.…

Black blood delayed enhancement magnetic resonance imaging

Technnology Duke University is seeking a corporate partners to commercialize a method of improved detection of infarcted heart tissue. The technology provides a dark blood delayed enhancement technique that improves the visualization of subendocardial infarcts…