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Breast cancer risk prediction technology using genomic classifier
Unmet Need The earliest form of breast cancer, ductal carcinoma in situ (DCIS), is diagnosed in almost 50,000 people in the U.S. each year. DCIS is considered noninvasive, as abnormal cells have not spread out…
A smartphone-based detector for mobile health applications
Unmet Need It is estimated that there are over 6 billion smartphone users worldwide, which translates to almost 83% of the world’s population. Due to their widespread use, smartphones present a golden opportunity to redefine…
Genomic Biomarkers of Locally Advanced Breast Cancer (LABC) and Inflammatory Breast Cancer (IBC)
Unmet Need Locally advanced breast cancer (LABC) and inflammatory breast cancer (IBC) are associated with high 5-year mortality rates (respectively 55% and 33%), especially when compared to early-stage breast cancers (~80%). LABC and IBC are…
All dielectric absorber for improved real-time imaging in the terahertz spectrum
Value Proposition Discoveries over the past decades have unveiled unique characteristics of the far-infrared or terahertz (THz) spectrum spanning from 0.3 THz to 10 THz, including non-ionization of biological materials, easy penetration into dielectric and…
A genomics-based method to identify cancer patients that will benefit from immune checkpoint therapy
Unmet Need Non-small-cell lung cancer accounts for 82% of all lung cancer diagnoses. Immune checkpoint blockade treatment is an exciting new course of action among advanced stage non-small-cell lung cancer patients. However, only a minority…
Bio Layer Interferometry Probe (BLIP) for in-vivo analyte detection
Unmet Need Diagnostic tests play a critical role in the clinical diagnosis, management, and monitoring of disease. These tests are designed to analyze biological specimens to identify analytes of interest by employing highly specific and…
Parametrization of fractal signature data
The risk of knee osteoarthritis progression can be predicted from the subtle characteristics revealed on a knee radiograph of the subchondral bone, i.e. bone that underlies the articular cartilage. This technology is software code to…
Detecting and predicting progression of osteoarthritis by biomarker analysis
Unmet Need Osteoarthritis (OA) is a prevalent chronic disease that impacts 32.5 million US adults and hundreds of millions worldwide. Further, global incidence of OA is increasing due to rises in geriatric populations and other…
Surface acoustic wave based separation techniques
Value Proposition Complex biofluids such as blood, urine etc. contain a plethora of particles of interest that are of diagnostic and research interest. Examples of such particles may include exosomes, or Circulating Tumor Cells (CTC).…
HIV-1 incidence biomarkers
Background Measures of HIV incidence are used to help public health officials, researchers, and policy makers monitor the epidemic, evaluate the impact of interventions, and assist in the identification of sites for HIV prevention trials.…
Method to trap and transport small particles with acoustic forces
Value Proposition Acoustic tweezers use ultrasound to create radiation force potential wells that enable precise and contact-free manipulation of physical and biological objects across a broad object size range. It is a fast-developing platform that…
Wearable device for early detection of influenza and common cold
Unmet Need Approximately 10% of the US population is infected with influenza each year resulting in 3 to 5 million severe cases and up to 500,000 deaths. Early detection of influenza-like illness can limit the…