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Text-based cessation program for smokeless tobacco users in underserved communities

Text-based cessation program for smokeless tobacco users in underserved communities

Unmet Need There is a need for accessible, scalable, and effective smokeless tobacco cessation programs tailored to rural and medically underserved populations. Traditional interventions are often resource-intensive, web-dependent, or inaccessible due to limited internet access,…

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Microbial Growth Foundational Model

Microbial Growth Foundational Model

Unmet Need Microbial growth dynamics provide crucial insights into microbial populations, with applications in drug discovery, personalized medicine, and synthetic biology. Advances in the field have resulted in an ever-growing list of known microbe species…

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A predictive model for early detection of psychiatric risk in adolescents

A predictive model for early detection of psychiatric risk in adolescents

Unmet Need According to the World Health Organization, nearly 15% of adolescents (10 to 19-year-olds) experience a mental health condition, many of which remain undiagnosed and untreated. Since the beginning of the COVID-19 pandemic, the…

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Computer Aided Detection Tool for Difficult-to-Detect Brain Metastases

Computer Aided Detection Tool for Difficult-to-Detect Brain Metastases

Unmet Need An estimated 20% of all cancer patients will develop brain metastases in their lifetime. These metastases are first diagnosed by neuroradiologists using CT, and more commonly, MR imaging. If a limited number of…

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Personalized Behavioral Risk Prediction Technology

Personalized Behavioral Risk Prediction Technology

Unmet Need Daily environments significantly influence mental and physical health, impacting factors like stress, sleep quality, and behaviors tied to addiction and mental health conditions. For example, specific environments may trigger smoking, exacerbate insomnia, or…

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Morphological multiparameter filtration and persistent homology in mitochondrial image analysis

Morphological multiparameter filtration and persistent homology in mitochondrial image analysis

Unmet Need Current mitochondrial network analysis tools require significant manual intervention, making them labor-intensive, subjective, and prone to variability. These limitations hinder the reproducibility and accuracy needed for studying complex mitochondrial morphologies in disease diagnostics,…

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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…

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Dark-Blood Delayed-Enhancement MRI: Improved Tissue Contrast and Blood-Pool Signal Suppression

Dark-Blood Delayed-Enhancement MRI: Improved Tissue Contrast and Blood-Pool Signal Suppression

Unmet Need Delayed-enhancement MRI (DE-MRI) is the standard for imaging myocardial infarction (MI), providing high-resolution maps of infarcted and viable myocardium. However, DE-MRI often suffers from poor differentiation between infarcted myocardium and the bright left…

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Machine learning algorithm to improve performance of hearing aids and cochlear implants in reverberant environments

Machine learning algorithm to improve performance of hearing aids and cochlear implants in reverberant environments

Unmet Need In the US, nearly 30 million adults require assistive hearing technology such as hearing aids and cochlear implants. Even with assistive devices, hearing impaired individuals have particular trouble with speech recognition in reverberant…

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The Chronic Overlapping Pain Condition Screener

The Chronic Overlapping Pain Condition Screener

Unmet Need Ten Chronic Overlapping Pain Conditions (COPCs) are currently recognized by the National Institutes of Health Pain Consortium (eg, irritable bowel syndrome, chronic migraine headache, and chronic low back pain). These conditions affect millions…

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Novel Self-Assembling Nanoparticles for Extended Duration Local Anesthetics

Novel Self-Assembling Nanoparticles for Extended Duration Local Anesthetics

Unmet Need An estimated 40 million surgeries are performed every year in the United States. Out of this population, an estimated 80% had post-operative pain with 75% reporting it as moderate to extreme. Local anesthetics…

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Automated drug diversion surveillance software

Automated drug diversion surveillance software

Unmet Need Drug diversion is a prevalent issue, among medical professionals. In addition to contributing to the opioid epidemic and causing infection outbreaks, drug diversion costs a yearly $70 billion within the healthcare industry alone.…

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