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Rapid, responsive, and active dissection insertion device for large-bore chest tubes
Unmet Need Tube Thoracostomy, a critical procedure for removing fluids and air from around the lungs and heart, has a high complication rate of 20% due to the technical skill required and anatomical differences between…
Clinically-Linked ECG and Arrhythmia Repository (CLEAR)
Invention Summary Duke inventors have developed a database of digital 12- lead ECG samples that represent key rhythms of cardiac disorders. Each patient’s disorder was validated by a licensed and board-certified cardiovascular medicine physician to…
Transcriptional alterations during blood storage to monitor stored red cells and reduce storage-lesions
Unmet Need Currently, red blood cell (RBC) testing focuses on factors such as hemoglobin content, RBC count, blood typing, and antibody content. These tests, though comprehensive, do not measure the health and quality of RBCs.…
Wearable smart radiation reporting material
Unmet Need Excess radiation exposure can result in DNA damage and tissue injury. Individuals who are occupationally exposed to ionizing radiation need to monitor and track radiation exposures. Small, personal radiation dosimeters currently exist, but…
A method for end-to-end spatial accuracy quality assurance for radiosurgery
Unmet Need Radiation therapy is an essential element of cancer treatment that benefits 4 million diagnosed patients every year. The ability to deliver complex three-dimensional distributions of dose that conform to even irregularly shaped lesions…
Wearable device for early detection of influenza and common cold
Unmet Need Approximately 10% of the US population is infected with influenza each year resulting in 3 to 5 million severe cases and up to 500,000 deaths. Early detection of influenza-like illness can limit the…
A system and method for planning radiosurgery treatments that can better target multiple tumors simultaneously
Unmet Need Brain metastases are the most common neurological complication of primary cancer and are estimated to occur in 9-17% of all cancer patients. Radiosurgery has become a standard treatment technique for brain metastases, which…
A Nano-scintillator fiber optic dosimeter device for accurately measuring radiation during brachytherapy
Value Proposition Two-thirds of all cancer patients receive radiation therapy. However, their radiation dose safety is not currently assured in the clinic. Medically relevant estimations of patient radiation doses received for a specific form of…
Scintillation materials and devices for high-resolution, high-sensitivity, ionizing radiation detectors
Value Proposition Many industries require radiation detection; everything from agriculture to oncology to manufacturing. The proposed Nano-scintillator Fiber Optic Dosimeter (NS-FOD) offers accurate radiation detective in an inexpensive and durable detector. The detector offers a…
Passive pressure sensor
Value proposition Monitoring Intracranial Pressure (ICP) in patients undergoing neurological conditions is critical in tracking progress and recovery. In conditions such as hydrocephalus, a shunt is used to allow extra cerebrospinal fluid to drain. These…