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Rapid, responsive, and active dissection insertion device for large-bore chest tubes

Rapid, responsive, and active dissection insertion device for large-bore chest tubes

Unmet Need Tube Thoracostomy, a critical procedure for removing fluids and/or air from around the lungs to restore breathing, has a high complication rate of 30%, with complications increasing cost by up to 21x. This…

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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…

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Spine Secure’s Non-Invasive Halo

Spine Secure’s Non-Invasive Halo

Unmet Need Globally, over 15 million people are living with spinal cord injury as of 2021. Based on data from 2019, 0.9 million new cases emerged in a year. While most cases are due to…

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Lightweight, portable wearable device for passive hand and wrist rehabilitation with adjustable therapy settings

Lightweight, portable wearable device for passive hand and wrist rehabilitation with adjustable therapy settings

Unmet Need Stroke, a prevalent cerebrovascular disease affecting 7.8 million patients in the US, often leaves survivors with hemiparesis, impacting the upper extremity on one side. About 85% of stroke patients experience reduced hand motor…

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Transcranial magnetic stimulation treatment for focal hand dystonia

Transcranial magnetic stimulation treatment for focal hand dystonia

Unmet Need Focal hand dystonia (FHD) is an involuntary movement disorder that occurs in an estimated 15 out of 1 million people. It causes sustained or intermittent muscle contractions that make it painful for people…

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Optically transparent model kidney for surgical simulation

Optically transparent model kidney for surgical simulation

Unmet Need Surgical simulation is an important step in medical training. It is particularly critical for training in the urological field, which had 144 residency programs in 2023. Lithotripsy, a surgical procedure to treat kidney…

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A microscopy method for acquiring polarization-sensitive phase information in 3D

A microscopy method for acquiring polarization-sensitive phase information in 3D

Unmet Need The majority of biological research and clinical diagnostics has involved the use of optical imaging systems for transparent specimens that rely on scalar properties like phase contrast. These systems have proved useful for…

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Long extra-corporeal arterial sheaths and catheters for coronary angiography and intervention

Long extra-corporeal arterial sheaths and catheters for coronary angiography and intervention

Value Proposition Percutaneous coronary interventions (PCI) such as angioplasty and angiography can be performed for therapeutic as well as diagnostic reasons. Over 20 million angiography and 10 million angioplasty procedures are projected to be performed…

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A drug-infused hydrogel implant for glaucoma drainage devices

A drug-infused hydrogel implant for glaucoma drainage devices

Unmet Need Glaucoma is an ocular disease involving heightened eye pressure most commonly leading to blindness, affecting roughly 3 million Americans. Current treatments include anti-steroidal or anti-inflammatory drugs to remove excess ocular fluid or decrease…

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A smartphone-based detector for mobile health applications

A smartphone-based detector for mobile health applications

Unmet Need It is estimated that there are over 6 billion smartphone users worldwide, which translates to almost 83% of the world’s population. Due to their widespread use, smartphones present a golden opportunity to redefine…

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Efficient scan patterns for scanning laser microscopy systems

Efficient scan patterns for scanning laser microscopy systems

Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…

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Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy

Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy

Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…

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