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Wearable smart radiation reporting material

Wearable smart radiation reporting material

Unmet Need Excess radiation exposure can result in DNA damage and tissue injury. Individuals who are occupationally exposed to ionizing radiation need to monitor and track radiation exposures. Small, personal radiation dosimeters currently exist, but…

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A synergistic chemotherapy and radiotherapy drug delivery technology for treating prostate cancer tumors

A synergistic chemotherapy and radiotherapy drug delivery technology for treating prostate cancer tumors

Unmet Need Pancreatic cancer is one of the deadliest manifestations of cancer in clinical oncology. Despite accounting for only 3.2% of all cancer cases, it is the third leading cause of cancer-related mortality. National Comprehensive…

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Tunable elastomer-like polymers for use in soft tissue regeneration and drug delivery

Tunable elastomer-like polymers for use in soft tissue regeneration and drug delivery

Unmet Need Biodegradable synthetic polymers are often used as scaffolding or support materials in tissue engineering and regenerative medicine. However, many of the materials that have been used widely, such as PLLA and PCL, do…

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Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications

Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications

Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 22.0% predicted to occur until 2024. Medical and dental products account for about…

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All dielectric absorber for improved real-time imaging in the terahertz spectrum

All dielectric absorber for improved real-time imaging in the terahertz spectrum

Value Proposition Discoveries over the past decades have unveiled unique characteristics of the far-infrared or terahertz (THz) spectrum spanning from 0.3 THz to 10 THz, including non-ionization of biological materials, easy penetration into dielectric and…

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Biomaterial therapy for healing brain tissue after ischemic stroke

Biomaterial therapy for healing brain tissue after ischemic stroke

Unmet Need Ischemic stroke affects 692,000 patients annually in the United States, and can result in paralysis and complications related to cognition and motor function. After a stroke, scarring and atrophy can occur at the…

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Biomaterial pouch for long-term xenogeneic cell transplantation

Biomaterial pouch for long-term xenogeneic cell transplantation

Unmet Need Cell therapy is an exciting therapeutic approach that is growing rapidly – there are more than 1,000 cell therapy clinical trials that are currently active in many different fields like oncology, neurology, hematology,…

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Enzymatic synthesis of aptamer-targeted polynucleotide drug delivery platforms for cancer therapy

Enzymatic synthesis of aptamer-targeted polynucleotide drug delivery platforms for cancer therapy

Unmet Need In the United States alone, over 1.8 million new patients were diagnosed with cancer in 2021, and over 600,000 patients died from the disease. Cytostatic nucleotides, such as gemcitabine and 5-fluorouracil, have been…

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A class of biodegradable stealth polymers to improve drug delivery

A class of biodegradable stealth polymers to improve drug delivery

Unmet Need Delivery of drugs or therapeutics such as small molecules, peptides, and proteins, in their native form, is limited by their poor stability, low solubility, and short in vivo circulation. These challenges in drug…

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An injectable hydrogel scaffold that delivers gene therapies locally

An injectable hydrogel scaffold that delivers gene therapies locally

Unmet Need Gene therapy has applications ranging from tissue engineering to vaccine development to infectious disease. Most approaches to deliver nucleic material involve the systemic intravenous delivery of condensed nucleic acid (e.g., within a virus…

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An implanted biomaterial to accelerate bone healing

An implanted biomaterial to accelerate bone healing

Unmet Need A leading concept in regenerative medicine is transplantation of tissue-specific cells, often supported with biomaterials, to promote tissue repair. While this strategy has achieved some success, its broad clinical application is hindered by…

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Peptide materials for immunomodulation

Peptide materials for immunomodulation

Value Proposition Glatiramoids are biomaterials synthesized for use as immunomodulators. Specifically, they are polypeptide mixtures with randomized amino acid sequences. Glatiramoids are currently FDA approved for use in multiple sclerosis. They have also been explored…

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