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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones
Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…
Acoustofluidic technologies for precision control in microfluidic systems
Unmet Need Achieving precise manipulation of particles, cells, and droplets in microscale liquid systems is a major challenge in life sciences, material sciences, and chemistry. Traditional microfluidic systems, which use hydrophobic channels and pressure differentials…
An automated system for dermatological laser surgery
Value Proposition Laser-based devices show promise for highly effective treatment of a range of cutaneous applications, including skin rejuvenation, tattoo removal, hair removal, vascular and pigmented lesions, and even skin cancers. During these procedures, a…
Rapid non-invasive optical assay system for intraoperative breast tumor margin assessment
Unmet Need Breast cancer is the most common non-skin cancer in women in the United States, accounting for 1 in 3 of all new female cancers each year. Breast conserving surgery is a common treatment…
Biodegradable, elastomeric copolymers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 22.0% predicted to occur until 2024. Medical and dental products account for about…
An artificial intelligence powered direct prediction model of machine parameters to enhance patient specific pre-treatment during radiation therapy
Unmet Need Intensity modulated radiation therapy (IMRT) and volumetric modulated radiation therapy (VMAT) are commonly used radiation therapy techniques that are characterized by their highly conformal dose distributions and require pre-treatment quality assurance to ensure…
A high-speed echocardiographic system that can assess cardiac function in real-time
Unmet Need Since its inception in the mid-1970s, real-time echocardiography employing phased array principles has had a significant impact on the practice of medicine particularly in cardiology. The real-time or live nature of image formation…
A system for expanding the available photon energies in radiation therapy
Unmet Need Radiation treatments are mostly delivered using a medical linear accelerator (linac). Currently, because of the complexity of the linac engineering and the requirement of the dose rate output, the standard design of a…
SYMPHONY: Synergistic Immuno Photothermal Nanotherapy
Unmet Need Metastatic spread results in more than 90 percent of cancer deaths, and current therapeutic options, such as systemic chemotherapy, are often ineffective with harsh side effects. In recent years, immunotherapy using specific immune…
A Nano-scintillator fiber optic dosimeter device for accurately measuring radiation during brachytherapy
Value Proposition Two-thirds of all cancer patients receive radiation therapy. However, their radiation dose safety is not currently assured in the clinic. Medically relevant estimations of patient radiation doses received for a specific form of…
A device design intended to reduce sound emissions during transcranial magnetic stimulation (TMS)
Unmet Need Transcranial magnetic stimulation (TMS) allows non-invasive stimulation of neurons in the brain using strong, brief magnetic pulses that induce electrical currents in neurons. TMS is widely used for probing brain function and it…
Fiber optic probes with self-calibration capability for tissue optical spectroscopy
Value Proposition UV-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) is sensitive to the absorption and scattering properties of biological molecules in tissue and thus can be used as a noninvasive in vivo tool to obtain quantitative…