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Auto-aligning slit lamp for eye exams
Unmet Need At least 2.2 billion people in the world have vision impairment. In 2019, there were 60 million incident cases and 438.4 thousand years lived with disability of eye injury. Almost half of these…
Auto-aligning handheld optical coherence tomography probe
Unmet Need Optical coherence tomography (OCT) is an optical imaging modality that uses low-coherence light to non-invasively obtain high resolution ocular images of structures including the retina and optic nerve. OCT has advantages over other…
Non-invasive peripheral retinal scanner using OCT
Unmet Need Images and light that sporadically appear in an individual’s visual field are known as “Flashes and floaters.” These optical aberrations bring approximately 150,000 patients in for eye exams each year in the United…
Gene therapy for Crb1 retinopathies
Value Proposition Current treatments for retinal disease include laser surgeries, injectable corticosteroids, and other medications which may slow the process of retinal degeneration but are not able to stop it. The Crb1 protein has been…
A drug-infused hydrogel implant for glaucoma drainage devices
Unmet Need Glaucoma is an ocular disease involving heightened eye pressure most commonly leading to blindness, affecting roughly 3 million Americans. Current treatments include anti-steroidal or anti-inflammatory drugs to remove excess ocular fluid or decrease…
An optical coherence tomography system capable of automatically and accurately imaging eyes without the use of chinrests
Unmet Need Optical coherence tomography (OCT) has revolutionized structural imaging in the eye’s anterior segment and retina. Ophthalmologists now routinely employ OCT in managing ocular diseases, including age-related macular degeneration, diabetic retinopathy, glaucoma, and corneal…
Automatic segmentation software to diagnose retinopathy of prematurity (ROP) from optical coherence tomography images in preterm infants
Unmet Need Retinopathy of prematurity (ROP) is a developmental vascular proliferative disorder that occurs in approximately 50-70% of preterm infants and is a leading cause of childhood blindness. The most critical factor in identifying ROP…
Efficient scan patterns for scanning laser microscopy systems
Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…
Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy
Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…
Gene therapy for long-term decrease of intraocular pressure
Unmet Need It is estimated that in the US alone, approximately 3 million individuals are living with glaucoma, making it the leading cause of blindness in the US. There currently is no cure for glaucoma,…
Novel system for improved aiming during optical coherence tomography imaging of young children
Unmet Need When a retinal condition is suspected in a patient, optical coherence tomography (OCT) is used to obtain detailed images of the retina. Due to the large amount of data needed to be processed…
Systems and methods to noninvasively enhance the visual acuity for patients with retinal prostheses
Unmet Need Degenerative eye diseases lead to a profound decrease in quality of life, and their incidence is on the rise. In high- and middle-income countries, age-related macular degeneration is the main and growing cause…