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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones

Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…

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Gene signature for prediction of acute rejection in kidney transplant

Gene signature for prediction of acute rejection in kidney transplant

Unmet Need Kidney transplant is the best current treatment for kidney failure. The kidney is the most common organ to be transplanted, and in 2019 there were 23,405 kidney transplants in the United States. Unfortunately,…

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Optically transparent model kidney for surgical simulation

Optically transparent model kidney for surgical simulation

Unmet Need Surgical simulation is an important step in medical training. It is particularly critical for training in the urological field, which had 144 residency programs in 2023. Lithotripsy, a surgical procedure to treat kidney…

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Deep learning segmentation of glomeruli on kidney frozen sections

Deep learning segmentation of glomeruli on kidney frozen sections

Value Proposition The conventional assessment of cadaveric donor kidneys by light microscopy is known to include several limitations. First, pathologists are required to travel to the site of explant at all times of the day…

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Method and apparatus for generating a steerable and non-axisymmetric pressure field in a shock wave lithotripter

Method and apparatus for generating a steerable and non-axisymmetric pressure field in a shock wave lithotripter

Unmet Need A lithotripter is a device used to noninvasively break up kidney stones using electromagnetic shock waves in a water bath. Lithotripters provide an advantage over surgical means by allowing for stones to be…

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A gene implicated in the causation of kidney disease

A gene implicated in the causation of kidney disease

Duke University is seeking a company interested in commercializing a risk assessment test and/or a therapeutic product targeting a gene which has been implicated in Glomerulonephritis. Focal and segmental glomeruloschlerosis (FSGS) is a significant cause…

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