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Intravesical UTI vaccine to induce bacteria-eradicating immune responses in the bladder
Unmet Need Urinary tract infections (UTI) are typically caused by uropathogenic E. coli (UPEC) that proliferate in urine and infect the urethra and bladder epithelial cells. UTIs represent the second most common bacterial infection in…
Inhibition of NLRP3 inflammasome to treat bladder inflammation
Unmet Need Benign prostatic hyperplasia, also known as prostate gland enlargement, commonly results in bladder outlet obstruction, BOO, and affects tens of millions of older men globally. Over 14 million men in the United States…
Electro-stimulation device to promote bladder voiding
Value Proposition Despite its association with a diverse array of conditions and particularly high prevalence among the elderly, underactive bladder lacks reliable clinical treatment options. Many pharmacological treatments have proven ineffective and cause undesirable side…