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3D cavitation mapping to improve laser lithotripsy for the treatment of kidney stones
Unmet Need The prevalence of kidney stones is on the rise, having increased from approximately 4% in the 1970s to nearly 10% today. Approximately 1 in 10 of Americans will experience a kidney stone in…
Optically transparent model kidney for surgical simulation
Unmet Need Surgical simulation is an important step in medical training. It is particularly critical for training in the urological field, which had 144 residency programs in 2023. Lithotripsy, a surgical procedure to treat kidney…
Intravesical UTI vaccine to induce bacteria-eradicating immune responses in the bladder
Unmet Need Urinary tract infections (UTI) are typically caused by uropathogenic E. coli (UPEC) that proliferate in urine and infect the urethra and bladder epithelial cells. UTIs represent the second most common bacterial infection in…
Inhibition of NLRP3 inflammasome to treat bladder inflammation
Unmet Need Benign prostatic hyperplasia, also known as prostate gland enlargement, commonly results in bladder outlet obstruction, BOO, and affects tens of millions of older men globally. Over 14 million men in the United States…