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Muscle-targeted gene therapy for SLC25A4 mitochondrial deficiency
Unmet Need There is a significant unmet need for disease-modifying therapies that address mitochondrial dysfunction in inherited cardiomyopathies and myopathies such as SLC25A4 deficiency. Existing treatments are limited to supportive care and heart transplantation, with…
Gene therapy and small molecule treatment of chronic pain without addiction
Unmet Need Chronic pain is an escalating issue worldwide – in the U.S., an estimated one of five adults are affected. Chronic pain is difficult to treat, often requiring powerful opioids to provide relief. These…
Nonlinear system model and method for computing and optimizing athletic performance and rehabilitation
Value Proposition Training is widely accepted as a method to improve one’s performance in sports. However, athletes typically have to rely on experience, heuristics, and rough approximations to design their training routines. Despite tremendous advances…