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An optical coherence tomography system capable of automatically and accurately imaging eyes without the use of chinrests
Unmet Need Optical coherence tomography (OCT) has revolutionized structural imaging in the eye’s anterior segment and retina. Ophthalmologists now routinely employ OCT in managing ocular diseases, including age-related macular degeneration, diabetic retinopathy, glaucoma, and corneal…
Automatic segmentation software to diagnose retinopathy of prematurity (ROP) from optical coherence tomography images in preterm infants
Unmet Need Retinopathy of prematurity (ROP) is a developmental vascular proliferative disorder that occurs in approximately 50-70% of preterm infants and is a leading cause of childhood blindness. The most critical factor in identifying ROP…
Efficient scan patterns for scanning laser microscopy systems
Unmet Need Scanning imaging systems, such as confocal scanning laser ophthalmoscopy (cSLO), hold great promise in the clinic to diagnose a variety of retinal disease like diabetic retinopathy. These systems are particularly promising for applications…
Feature-Guided Image Fusion of Intrasurgical Optical Coherence Tomography and Digital Surgical Microscopy
Unmet Need Eye surgery is a high-impact intervention necessary to preserve the sight of thousands of patients, with retinal detachment surgeries alone constituting approximately 28,000 cases per year in the United States alone. Microscope-integrated optical…
Systems and methods to noninvasively enhance the visual acuity for patients with retinal prostheses
Unmet Need Degenerative eye diseases lead to a profound decrease in quality of life, and their incidence is on the rise. In high- and middle-income countries, age-related macular degeneration is the main and growing cause…
Making quantitative measurements of intraocular structures with optical coherence tomography
Unmet Need Recent advancements in intraoperative optical coherence tomography (OCT) have significantly improved visualization of tool-tissue interactions inside the eye. Visually assisted procedures are becoming effective treatments for previously untreatable genetic or degenerative retinal diseases.…
A handheld, low-cost confocal scanning laser ophthalmoscope for remote screening and telemedicine applications
Unmet Need Diabetic retinopathy (DR) is the leading cause of blindness in working age adults affecting approximately 100 million people worldwide. Studies show that early detection and treatment can reduce the risk of blindness by…
An optical system to improve glaucoma diagnosis and treatments by monitoring the ocular outflow pathway in vivo
Unmet Need Glaucoma, a progressive optic neuropathy, is a leading cause of blindness in this country and the rest of the world. The root cause of primary glaucoma is poorly understood, but risk factors have…
Techniques for the segmentation of layered structures using graph theory and dynamic programming
Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges.…
Automated segmentation of layered structures such as retinal layers using graph cuts
Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges.…