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Fiber optic probe with integrated photodetector capabilities
Unmet Need Light-based diagnostics is a non-intrusive procedure that can be used to monitor chemotherapy treatment efficacy. Optical imaging additionally has the capacity for roles in diagnosis and surgery guidance. Currently, many devices for optic…
All dielectric absorber for improved real-time imaging in the terahertz spectrum
Value Proposition Discoveries over the past decades have unveiled unique characteristics of the far-infrared or terahertz (THz) spectrum spanning from 0.3 THz to 10 THz, including non-ionization of biological materials, easy penetration into dielectric and…
A method for end-to-end spatial accuracy quality assurance for radiosurgery
Unmet Need Radiation therapy is an essential element of cancer treatment that benefits 4 million diagnosed patients every year. The ability to deliver complex three-dimensional distributions of dose that conform to even irregularly shaped lesions…
A method for validating complex radiation treatments using 3D dosimetry that can be implemented remotely
Unmet Need Radiation therapy is an essential element of cancer treatment that has been estimated to be potentially beneficial to 4 million diagnosed patients every year. The advent of commercially available magnetic resonance imaging guided…
An optical scanning system that reduces the planning cost associated with 3D dosimetry planning techniques
Unmet Need Radiation therapy is an essential element of cancer treatment that has been estimated to be potentially beneficial to 4 million diagnosed patients every year. Since the turn of the millennium, the sophistication, precision,…
Performing tissue discrimination for cancer diagnostics using X-ray diffraction imaging
Value Proposition Cancer diagnosis is a multi-step process involving a variety of specialties. Radiologists use macroscopic imaging systems to determine where to look for potential cancer, while pathologists use microscopic imaging to confirm cancer at…
Fiber optic probes with self-calibration capability for tissue optical spectroscopy
Value Proposition UV-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) is sensitive to the absorption and scattering properties of biological molecules in tissue and thus can be used as a noninvasive in vivo tool to obtain quantitative…
Optical device for in vivo assessment of tissues
Value Proposition Fluorescence and diffuse reflectance spectroscopy in the ultraviolet-visible (UV-VIS) spectrum are increasingly being investigated for tissue characterization. These biological scatterers, absorbers, and fluorophores may be used to indicate the existence of certain diseases.…
A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue
Value Proposition Fluorescence spectroscopy has been used successfully to discriminate premalignancy and malignancy in a number of organ sites. However, due to the complex interplay of absorption, scattering, and fluorescence in tissue, it is difficult…
Magnetic resonance imaging-based tool to predict breast cancer recurrence
Value Proposition Breast cancer is a leading cancer diagnosis among women with over 270,000 new cases every year in the United States. Breast cancer comprises a diverse collection of diseases with varying genomic signatures and…
Optimization of fiber optic probes for spectroscopic measurements
Value Proposition Early detection of cancer greatly increases the chances for a positive outcome. The World Health Organization states that there are two major components of early detection of cancer: increased awareness and screening. Diffuse…