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Showing 5 matches for the following: Inventor: "McDonnell, Donald" ×
Melanoma treatment method using estrogen modulating small molecules
Unmet Need Metastatic melanoma, skin cancer that has spread, is an incredibly deadly cancer, with a median survivorship of 6-9 months. For patients with melanoma, a frequently used therapy is immune checkpoint blockade (ICB). These…
CaMKK2 as a target for cancer immunotherapy
Tumor cells have the remarkable ability to block the immune system, and in such a way escape the immune response. This is a major problem that causes cancer development and metastasis. The ability of tumor…
Novel therapeutic targets in the androgen receptor signaling pathway for prostate cancer
Unmet Need Prostate cancer is the most common malignancy in men. The most recent CDC data demonstrates that prostate cancer makes up 12.2% all new cancer cases in the U.S. at 207,430. Prostate cancers express…
A reporter gene C3-T1ba
Reporter Gene used to measure both estrogen and tamoxifen activated estrogen receptor transcriptional activity reconstituted in mammalian cells. Derived from the complement 3 (C3) promotor.