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Leukocyte phenotyping methods to provide prognostic information and risk/resilience stratification for surgical procedures and critical illness

Leukocyte phenotyping methods to provide prognostic information and risk/resilience stratification for surgical procedures and critical illness

Unmet Need It is estimated that surgical complications arise in 16.4%, or almost 1 in 6 surgical procedures in the United States. Most complications have an immunological basis related to infection or aberrant adaptation to…

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A genomics-based method to identify cancer patients that will benefit from immune checkpoint therapy

A genomics-based method to identify cancer patients that will benefit from immune checkpoint therapy

Unmet Need Non-small-cell lung cancer accounts for 82% of all lung cancer diagnoses. Immune checkpoint blockade treatment is an exciting new course of action among advanced stage non-small-cell lung cancer patients. However, only a minority…

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Components of the Wnt-Beta-catenin paracrine signaling pathway as predictive biomarkers for cancer immunotherapy

Components of the Wnt-Beta-catenin paracrine signaling pathway as predictive biomarkers for cancer immunotherapy

Value Proposition Immunotherapy is a promising approach for the treatment of many cancers. However, despite early success, majority of patients with advanced cancer fail to respond or become resistant. In even the most immunogenic cancer…

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