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Bacterial voltage gated ion channels for cardiac reprogramming

Bacterial voltage gated ion channels for cardiac reprogramming

Unmet Need Untreated cardiovascular disease (CVD) can lead to irreversible heart damage. This occurs when ischemia — inadequate blood flow — leads to the death of heart muscle fibers that conduct electrical impulses. Consequently, scar…

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Blood pressure control by gene editing

Blood pressure control by gene editing

Unmet Need The World Health Organization estimates that high blood pressure (hypertension) results in approximately 9 million annual deaths worldwide. Currently available drugs used to control blood pressure can be effective but are limited by…

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A method for treating critical limb ischemia and other ischemic injuries

A method for treating critical limb ischemia and other ischemic injuries

Unmet Need The most severe stage of peripheral artery disease, a chronic vascular disease characterized by impaired circulation to patients’ lower extremities, is critical limb ischemia (CLI), and it affects approximately two million people in…

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Isolated organ viral, theraputic or cell therapy delivery

Isolated organ viral, theraputic or cell therapy delivery

Value proposition Cardiovascular diseases (CVD) remain the leading cause of death worldwide. The number of CVD patients with heart failure (HF) in the US is approaching 6.5 million adults and is estimated to increase by…

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