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A method for treating critical limb ischemia and other ischemic injuries
Unmet Need The most severe stage of peripheral artery disease, a chronic vascular disease characterized by impaired circulation to patients’ lower extremities, is critical limb ischemia (CLI), and it affects approximately two million people in…
Virtual frequency-selective inversion method for fat suppression in MRI
Unmet Need In magnetic resonance imaging (MRI), data is acquired by a scanner that sends a sequence of radio frequency (RF) pulses into the tissue placed in a strong magnetic field. The magnetic field causes…
A high-speed echocardiographic system that can assess cardiac function in real-time
Unmet Need Since its inception in the mid-1970s, real-time echocardiography employing phased array principles has had a significant impact on the practice of medicine particularly in cardiology. The real-time or live nature of image formation…
Harvis: an interactive virtual reality tool for modification and simulation of blood flow
Unmet Need Cardiovascular disease (CVD) is the largest underlying cause of mortality in the United States, causing one in every three deaths and costing an estimated $316 billion dollars a year. In recent years, computational…
A low-cost test for patients to self-monitor prothrombin time at home
Unmet Need Heart failure affects over 6.4 million individuals in the US, with over 550,000 new cases emerging annually. A large fraction of these cases requires long-term use of ventricular assist devices that necessitate the…
Cardiac rhythm interpretation flipbook
Unmet Need Nurses caring for patients who require ECG monitoring are trained in rhythm interpretation in order to identify normal and abnormal cardiac conditions and to apply appropriate therapeutic interventions. However, studies have shown a…
A new method to improve contrast-enhanced MRI by suppressing blood pool signal
Unmet Need In magnetic resonance imaging (MRI), contrast agents are often used to enhance the difference between diseased and normal tissue. Images taken with contrast agents allow to identify myocardial infarction, stroke, tumors, atherosclerosis, tissue…
Single-cardiac-cycle phase sensitive inversion recovery (PSIR) method for cardiac MRI
Unmet Need Magnetic Resonance Imaging (MRI) is a safe, non-invasive test that creates detailed images of organs and tissues. In a typical MRI procedure, the subject is positioned in a strong magnetic field, and the…
Peripherally Inserted Left Ventricular Vent and Anticoagulation System (PILVAS)
Value Proposition Extra-corporeal membrane oxygenation (ECMO) support is a rapidly growing technique to treat patients in severe cardiac distress. As its use increases, incidence of the common complications of support, including significant bleeding, stroke, infection,…
Treating and reducing cardiac dysfunction with bisphosphonate compositions by increasing the phosphorylation of kinases in heart tissue
Value Proposition The prevalence of heart failure (“HF”) has grown to epidemic proportions as the population ages. HF may be caused by many forms of heart disease. Each of these disease processes can lead to…
Treating heart failure with bisphosphonate compositions
Value Proposition The prevalence of heart failure (“HF”) has grown to epidemic proportions as the population ages and as cardiologists have become more successful at reducing mortality from ischemic heart disease, the most common prelude…
A simple metabolomic profile to predict risk of subsequent cardiovascular events
Value Proposition Coronary artery disease (CAD) is the leading cause of death in industrialized countries, and in concert with the epidemic of obesity and diabetes, is rapidly becoming the leading cause of death in developing…