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Methods to utilize microbial organisms in the gut to modulate neurological responses
Unmet Need The gut is home to dynamic bacterial communities that shape the behavior of the host. The food we eat, our changes in mood, and even some of our social behaviors correlate with shifts…
Chemical modulators of immune checkpoints and cell growth for cancer treatment
Unmet Need Each year there are over 1.6 million new cases of cancer in the US, and over 600,000 cases prove fatal. Treating various types of cancer can be particularly challenging because of the complex…
An effective method for treating functional gastrointestinal and motility disorders using patterned electrical stimulation in the colon
Unmet Need Functional gastrointestinal and motility disorders (FGIMD) impact 1 in 5 persons in the U.S. It is a group of disorders classified by GI symptoms which include irritable bowel syndrome, fecal incontinence, constipation, and…
Torque Assisting Device for Endoscopy
Unmet Need Colorectal cancer is the third leading cause of cancer-related deaths in the United States. As a preventative measure, more than 15 million colonoscopies are performed in the United States each year. This common…
A method of treating and preventing gastrointestinal disorders
Unmet Need Gastrointestinal disorders such as inflammatory bowel disease, constipation, and intestinal pseudo-obstruction have been estimated to affect more than 40% of adults worldwide. These disorders are often associated with alterations in gut microbiota, which…
A machine learning model to assess colorectal cancer risk using whole blood samples
Unmet Need Colorectal cancer is the third most commonly occurring cancer in men and the second in women. Early detection and treatment have contributed to an overall dropping of the death rate for several decades,…